Results 61 to 70 of about 2,031,954 (298)

The Role of Transdisciplinary Research for Agricultural Climate Change Adaptation Strategies

open access: yesAgronomy, 2018
While science widely acknowledges the necessity of climate change adaptation (CCA), concrete strategies for CCA by major land-use actor groups at a local level are largely missing.
Markus Schermer   +6 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

On Scenario Synchronization [PDF]

open access: yes, 2010
In software development a system is often viewed by various models at different levels of abstraction. It is very difficult to maintain the consistency between them for both structural and behavioral semantics. This paper focuses on a formal foundation for presenting scenarios and reasoning the synchronization between them.
Duc-Hanh Dang   +2 more
openaire   +2 more sources

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Investigating Integrated Approaches to Elderly Support for Tehrani Family in the Horizon of 1430 [PDF]

open access: yesپژوهشنامه مددکاری اجتماعی, 2018
One of the important issues facing Tehrani families is the protection of the elderly. Future demographic, family, economic, and cultural changes will add to those more complex dimensions.
jafar hezajaribi   +3 more
doaj   +1 more source

ISS-Scenario: Scenario-Based Testing in CARLA

open access: yes
The rapidly evolving field of autonomous driving systems (ADSs) is full of promise. However, in order to fulfil these promises, ADSs need to be safe in all circumstances. This paper introduces ISS-Scenario, an autonomous driving testing framework in the paradigm of scenario-based testing.
Renjue Li   +2 more
openaire   +3 more sources

Wake Vortex Scenarios Simulation Package for Take-Off and Departure [PDF]

open access: yes, 2012
The WakeScene-D software package (Wake Vortex Scenarios Simulation Package for Departure) has been developed for comprehensive airspace simulations of take-off and departure.
Kladetzke, Jan, Holzäpfel, Frank
core  

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Macroecology meets IPBES

open access: yesFrontiers of Biogeography, 2016
The Intergovernmental Platform for Biodiversity and Ecosystem Services (IPBES), established in 2012 to counter the biodiversity crisis, requires the best scientific input available to function as a successful science-policy interface that addresses the ...
Christian Hof   +10 more
doaj  

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