Results 41 to 50 of about 816,298 (267)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Development of Regulatory Strategies in the Sharing Economy: The Application of Game Theory

open access: yesEconomies, 2023
Regulating the sharing economy is one of the most important aspects in the development of a business model that has developed rapidly due to the widespread adoption of digital technologies and is closely linked to the fast pace of institutional changes ...
Anna Y. Veretennikova   +1 more
doaj   +1 more source

On Scenario Synchronization [PDF]

open access: yes, 2010
In software development a system is often viewed by various models at different levels of abstraction. It is very difficult to maintain the consistency between them for both structural and behavioral semantics. This paper focuses on a formal foundation for presenting scenarios and reasoning the synchronization between them.
Duc-Hanh Dang   +2 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Multimodal and Temporal Graph Fusion Framework for Advanced Phishing Website Detection

open access: yesIEEE Access
Phishing attacks are among the persistent threats that are dynamically evolving and demand advanced detection mechanisms to counter more sophisticated techniques.
S. Kavya, D. Sumathi
doaj   +1 more source

Merging Scenarios

open access: yesElectronic Notes in Theoretical Computer Science, 2005
AbstractThis paper proposes a merge operator for behavioral requirements expressed by Message Sequence Charts and shows how this product can be systematically used to integrate new behaviors in an existing one. First the merge operator is defined as a fibered product of scenario descriptions. This product is then used to integrate a consensus mechanism
Jacques Klein   +2 more
openaire   +2 more sources

Parameterized Dataflow Scenarios [PDF]

open access: yesIEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems, 2015
Although well-suited for capturing concurrency in streaming applications, purely dataflow-based models of computation are lacking in expressing intricate control requirements that many modern streaming applications have. Consequently, a number of modeling approaches combining dataflow and finite-state machines has been proposed.
Mladen Skelin   +3 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

EVALUATION OF WORLD ENERGY SCENARIOS

open access: yesVestnik MGIMO-Universiteta, 2016
What are the future global systems developments? It remains one the biggest unknown, especially in terms of energy, as it is globally considered as both cause and solution for multiple problems of the humanity. Therefore, nowadays a number of experts are
V. I. Salygin, I. I. Litvinyuk
doaj   +1 more source

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