Large‐Scale Machine Learning to Screen for Small‐Molecule Senolytics
Advanced Intelligent Discovery, EarlyView.A consistent workflow underpins all experiments in this study. A dedicated model‐selection dataset first identifies optimal hyperparameters for each algorithm. Models are then trained and rigorously evaluated on independent sets of molecules using the senolytic ratio SR. Comprehensive hyperparameter exploration across SMILES representations, task types,
Alexis Dougha +2 more
wiley +1 more source
AI, authorship teams and agency: Enacting fission and fusion. [PDF]
Med EducMaggio LA, Konopasky A.
europepmc +1 more source
A Critical Assessment of Bonding Descriptors for Predicting Materials Properties
Advanced Intelligent Discovery, EarlyView.The impact of new bonding descriptors in machine learning models for predicting material properties is assessed. Improvements are validated using significance tests, and new, intuitive descriptors for screening lattice thermal conductivity and projected force constants are introduced.
Aakash Ashok Naik +6 more
wiley +1 more source
Comparison of the 2024 National Institute for Health and Care Excellence sepsis guideline for adults against the 2016 guidelines: a service evaluation. [PDF]
Eur J Emerg MedBhattacharjee A, Bozorgi H, Boyle A.
europepmc +1 more source
A Hybrid Transfer Learning Framework for Brain Tumor Diagnosis
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.A novel hybrid transfer learning approach for brain tumor classification achieves 99.47% accuracy using magnetic resonance imaging (MRI) images. By combining image preprocessing, ensemble deep learning, and explainable artificial intelligence (XAI) techniques like gradient‐weighted class activation mapping and SHapley Additive exPlanations (SHAP), the ...
Sadia Islam Tonni +11 more
wiley +1 more source
Perspectives on the Influence of Pharmaceutical and MedTech Companies on Deprescribing Decisions and Conference Sponsorship: A Survey Study. [PDF]
Basic Clin Pharmacol ToxicolJungo KT +3 more
europepmc +1 more source
Calibration‐Free Electromyography Motor Intent Decoding Using Large‐Scale Supervised Pretraining
Advanced Intelligent Systems, EarlyView.Calibration‐free electromyography motor intent decoding is enabled through large‐scale supervised pretraining across heterogeneous datasets. A Spatially Aware Feature‐learning Transformer processes variable channel counts and electrode geometries, allowing transfer across users and recording setups. On a held‐out benchmark, fine‐tuned cross‐user models
Alexander E. Olsson +3 more
wiley +1 more source
Barriers to and enablers of prophylactic compression use by people at risk of venous leg ulcer recurrence: a qualitative study. [PDF]
BMJ OpenAlkahtani AM +3 more
europepmc +1 more source
Advanced Intelligent Systems, EarlyView.This study presents a novel framework that enhances the reliability of DNS traffic monitoring using a hybrid long short‐term memory‐deep neural network (LSMT‐DNN) architecture, enabling robust detection of adversarial DNS tunneling. The proposed framework leverages feature extraction from DNS traffic patterns, including domain request sequences, query ...
Ahmad Almadhor +5 more
wiley +1 more source