Results 101 to 110 of about 2,804,250 (299)

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti   +19 more
wiley   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner   +14 more
wiley   +1 more source

Airline Schedule Competition: Product-Quality Choice in a Duopoly Model [PDF]

open access: yes
This paper presents a simple model of airline schedule competition that circumvents the complexities of the spatial approach used in earlier papers. Consumers choose between two duopoly carriers, each of which has evenly spaced flights, by comparing the ...
Jan K. Brueckner, Ricardo Flores-Fillol
core  

Machine Learning Applied to High Entropy Alloys under Irradiation

open access: yesAdvanced Engineering Materials, EarlyView.
Designing alloys for extreme environments demands fast, trustworthy prediction. This review charts how machine learning—especially machine‐learned interatomic potentials and predictive models based on experiment‐informed datasets—captures the complexity of high‐entropy alloys in extreme environments, predicts phase formation, mechanical properties, and
Amin Esfandiarpour   +8 more
wiley   +1 more source

X‐Ray Computed Tomography Quantifies Primary Phases and Reveals Crack Morphology in High‐Cycle Fatigue of Aluminum Alloy EN AW‐2618A

open access: yesAdvanced Engineering Materials, EarlyView.
Primary phases and a fatigue crack are studied in a forged blank of an aluminum alloy using synchrotron and laboratory X‐ray computed tomography. To image the crack, the fatigue test is interrupted, and a static tensile load is applied to open the crack.
Jakob Schröder   +6 more
wiley   +1 more source

Mathematical modelling of hydraulic conditions of balancing and control of heating, cooling and dehumidification subsystem in ventilation and air conditioning systems [PDF]

open access: yesИнженерно-строительный журнал, 2011
The article is the second part of the one published in the Vol. 1, 2011. The aim of this research is processes modelling and investigation of quantity parameters influence on heating and cooling subsystem of VAC systems when balancing that subsystem by ...
A. G. Sotnikov, A. P. Rusakov
doaj  

Development and Preliminary In Vivo Study of 3D‐Printed Bioactive Glass Scaffolds with Trabecular Architecture

open access: yesAdvanced Engineering Materials, EarlyView.
This study reports the fabrication of trabecular bioactive glass scaffolds (composition “1d”: 46.1SiO2‐28.7CaO‐8.8MgO‐6.2P2O5‐5.7CaF2‐4.5Na2O wt%) through vat photopolymerization and the relevant results from mechanical testing and in vivo implantation procedures in rabbit femora, showing great promise for bone tissue engineering applications.
Dilshat Tulyaganov   +8 more
wiley   +1 more source

Micropatterned Biphasic Printed Electrodes for High‐Fidelity on‐Skin Bioelectronics

open access: yesAdvanced Functional Materials, EarlyView.
Micropatterned biphasic printed electrodes achieve unprecedented skin conformity and low impedance by combining liquid‐metal droplets with microstructured 3D lattices. This scalable approach enables high‐fidelity detection of ECG, EMG, and EEG signals, including alpha rhythms from the forehead, with long‐term comfort and stability.
Manuel Reis Carneiro   +4 more
wiley   +1 more source

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