Results 191 to 200 of about 1,680,593 (340)

PTf‐SRiApt Targeting SCAF4‐POLR2A Interaction Suppresses Tumor Growth and Promotes Antitumor Immunity in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A phosphorothioate‐modified aptamer PTf‐SRiApt capable of disrupting “undruggable” transcription factor SCAF4‐POLR2A interaction with high inhibitory activity and biological stability is presented here. Through this inhibition, PTf‐SRiApt successfully arrested cell cycle progression, induced cell death, and elevated immune recruitment in SCAF4‐POLR2A ...
Liyan Fei, Yichun Pan, Jie Zhai, Tongqing Li, Yuxin Zhou, Sheyu Zhang, Juan Wei, Qian Hu, Xueying Liu, Lu Guo, Weizhu Wu, Yong Wei, Qin Wu, Weihong Tan   +13 more
wiley   +1 more source

Contrasting effects of reinforcer rate and magnitude on differential resistance to change in humans. [PDF]

J Exp Anal Behav
Costa CE, da Silva KP, de Méo Luiz AC, Choinski AM, Lattal KA.   +4 more
europepmc   +1 more source

Decision CPM: A Method for Simultaneous Planning, Scheduling, and Control of Projects [PDF]

, 1967
Wallace B. Crowston, Gerald L. Thompson
openalex   +1 more source

Research Progress on Biomaterials with Immunomodulatory Effects in Bone Regeneration

Advanced Science, EarlyView.
This review highlights recent advanced in immunomodulatory biomaterials for bone repair, focusing on design strategies, immune interactions, and clinical potential. Abstract The immune system plays a pivotal role in bone regeneration, and biomaterials engineered to modulate immune responses present a promising strategy for the treatment of extensive ...
Jianan Li, Ying Qu, Bingyang Chu, Tingkui Wu, Meng Pan, Dong Mo, Lang Li, Yang Ming, Yun Yang, Meng Wang, Xinlong He, Zhiyong Qian   +11 more
wiley   +1 more source

Bibliometric Research on Surgical Scheduling Management from the Perspective of Web of Science

Journal of Multidisciplinary Healthcare
Ke Wang, Xuelu Wang, Chenying Xu, Lina Bai Operating Room, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine ...
Wang K, Wang X, Xu C, Bai L
doaj  

Predicting the Epidemiological Effects in the United Kingdom of Moving from PCV13 to PCV15 in the Routine Pediatric 1 + 1 Vaccination Schedule. [PDF]

Vaccines (Basel)
Oidtman RJ, Banniettis N, Weaver J, Matthews IR, Ntais D, Meleleo G, Malik TM, Lang JC, Sharomi O.   +8 more
europepmc   +1 more source

BRAIN STIMULATION AS A REINFORCER: INTERMITTENT SCHEDULES¹ [PDF]

, 1965
Stanley S. Pliskoff, James E. Wright, Tim Hawkins   +2 more
openalex   +1 more source

Piezo1 Activation Improves NSCLC Liver Metastasis Immunotherapy by Overriding Matrix Stiffness‐Mediated Bimodal PD‐L1/CXCL10 Regulation

Advanced Science, EarlyView.
This study demonstrates that Piezo1 activation enhances FAK‐YAP‐mediated upregulation of PD‐L1 and CXCL10, thereby promoting an immunotherapy‐responsive tumor microenvironment in NSCLC. Cyclic stretch modulates the PD‐L1/CXCL10 response to ECM stiffness, reshaping their expression dynamics.
Tian Zhang, Yuan Li, Bo Cheng, Zhao Xu, Mengjie Liu, Jinteng Feng, Yixue Bai, Yang Yu, Panpan Jiang, Luying Geng, Feng Xu, Hui Guo   +11 more
wiley   +1 more source

A bi-decision model for electric vehicle dispatch and battery swapping station charging schedule problem. [PDF]

Sci Rep
Su Y, Tian S, Wu H, Li X.
europepmc   +1 more source

RANDOM INTERVAL SCHEDULES OF REINFORCEMENT¹ [PDF]

, 1963
J. R. Millenson
openalex   +1 more source