Results 251 to 260 of about 3,480,656 (399)

Actionable Forecasting as a Determinant of Biological Adaptation

open access: yesAdvanced Science, EarlyView.
A new framework reveals how biological systems can achieve precise adaptation by tracking an actionable target that combines the current optimal state with its rate of change. This approach, implemented through dynamics‐informed neural networks, demonstrates that predictive mechanisms like circadian rhythms become beneficial when environmental sensing ...
Jose M. G. Vilar, Leonor Saiz
wiley   +1 more source

Monolithic 3D Oscillatory Ising Machine Using Reconfigurable FeFET Routing for Large‐Scalability and Low‐Power Consumption

open access: yesAdvanced Science, EarlyView.
This paper introduces a novel M3D Oscillatory Ising Machine (OIM) utilizing FeFETs as in‐memory routing switches and biristors as oscillators. The system achieves precise control, scalability, and low power consumption, solving complex optimization problems like MaxCUT problem.
Joon Pyo Kim   +8 more
wiley   +1 more source

A phase I, first-in-human trial of KO-947, an ERK1/2 inhibitor, in patients with advanced solid tumors. [PDF]

open access: yesESMO Open
Schram AM   +9 more
europepmc   +1 more source

Massage‐Mimicking Nanosheets Mechanically Reorganize Inter‐organelle Contacts to Restore Mitochondrial Functions in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li   +12 more
wiley   +1 more source

Immunization coverage and timeliness of vaccination in young patients with inborn errors of metabolism: a French multicentric study. [PDF]

open access: yesOrphanet J Rare Dis
Renous AS   +11 more
europepmc   +1 more source

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