Results 251 to 260 of about 763,342 (316)

7‐Ketodeoxycholic Acid Promotes Colonic Mucosal Healing by Inducing Calcium Release from Endoplasmic Reticulum via the TGR5‐IP3R Pathway

open access: yesAdvanced Science, EarlyView.
7‐KDCA functions by driving intestinal epithelial cell migration through induction of calcium release from the endoplasmic reticulum. The findings emphasize a previously unrecognized property of 7‐KDCA in regulating cell migration, a required process for effective epithelial restitution and repair that is particularly critical for patients with UC to ...
Jing Zhang   +9 more
wiley   +1 more source

The consequences of a compressed workweek: a systematic literature review. [PDF]

open access: yesInt Arch Occup Environ Health
Bernstrøm V   +4 more
europepmc   +1 more source

Conductive Microneedles Loaded With Polyphenol‐Engineered Exosomes Reshape Diabetic Neurovascular Niches for Chronic Wound Healing

open access: yesAdvanced Science, EarlyView.
This study establishes a bio‐electroceutical interface by synergizing engineered exosome‐derived biological signals with electroconductive microneedle‐delivered electrical cues, achieving dual‐pathway reprogramming of the diabetic neurovascular niches and accelerating wound healing. Abstract Diabetic wound healing remains a major clinical challenge due
Di Liu   +5 more
wiley   +1 more source

Decoy Extracellular Vesicles Overcome Triple‐Negative Breast Cancer Heterogeneity via Membrane‐Cytoplasm‐Mitochondria Cascade Targeting

open access: yesAdvanced Science, EarlyView.
siT/MOF@EVs overcome TNBC heterogeneity through a tumor cell membrane–cytoplasm–mitochondria cascade effect, triggering a self‐reinforcing anti‐tumor immune cycle and durable immune memory. The system enables sequential targeting of membrane checkpoints ligands (decoy effect), cytoplasmic siRNA delivery (CSC suppression), and mitochondrial MOF ...
Chuanrong Chen   +8 more
wiley   +1 more source

Optimal dosing of anti-cancer treatment under drug-induced plasticity. [PDF]

open access: yesNPJ Syst Biol Appl
Gunnarsson EB, Magnússon BV, Foo J.
europepmc   +1 more source

Prior human endemic coronavirus exposure does not affect humoral responses to SARS-CoV-2 protein vaccines. [PDF]

open access: yesNPJ Vaccines
de Bruyn G   +11 more
europepmc   +1 more source

Predicting the Epidemiological Effects in the United Kingdom of Moving from PCV13 to PCV15 in the Routine Pediatric 1 + 1 Vaccination Schedule. [PDF]

open access: yesVaccines (Basel)
Oidtman RJ   +8 more
europepmc   +1 more source

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