Results 251 to 260 of about 2,804,250 (299)

Optimal Sunitinib Dosing Based on Platelet Count in an Older Patient With Gastrointestinal Stromal Tumor. [PDF]

In Vivo
Suto H, Kawamura M, Morita M, Sakai H, Onoe T, Ikeuchi K, Matsumoto K.   +6 more
europepmc   +1 more source

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

Advanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
wiley   +1 more source

Boosting the influenza vaccine schedule in children with cancer: a prospective open-label study. [PDF]

NPJ Vaccines
Chiu SK, Furlong E, McKinnon EJ, Fox A, Ovando SS, Carolan L, McLean-Tooke A, Oommen J, Yeoh DK, Cheung LC, Gottardo NG, Kotecha RS.   +11 more
europepmc   +1 more source

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

Advanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou, Cheng‐Wei Ju, Nicholas A. Egan, Yanjun Wei, Yunfei Wang, Minghao Dang, Tianyi Zhou, Leilei Shi, Ningbo Zheng, Si Chen, Ashley M. Guerrero, Xiaofang Liang, Wanfu Wu, Areej Akhtar, Chitra Dhiman, Debanwita Roy Burman, Andro E. Gerges, Mason D. Flores, Han Li, Li‐Sheng Zhang, Marleen Kok, Xiaobo Mao, Linghua Wang, Qin Feng, Yiwen Chen, Sanghoon Lee, Daniel J. McGrail, Nidhi Sahni, Chuan He, Amir A. Jazaeri, Weiyi Peng   +30 more
wiley   +1 more source

Shift Schedule With Fewer Short Daily Rest Periods and Sickness Absence Among Health Care Workers: A Cluster Randomized Clinical Trial.

JAMA Netw Open
Djupedal ILR, Harris A, Svensen E, Lie SA, Wang ALH, Pallesen S, Waage S, Nielsen MB, Sunde E, Bjorvatn B, Holmelid Ø, Vedaa Ø.   +11 more
europepmc   +1 more source

Optimal Control of Immune Checkpoint Inhibitor Therapy in a Heart-Tumour Model. [PDF]

Bull Math Biol
van der Vegt SA, Baker RE, Waters SL.
europepmc   +1 more source

Ratoon Season Rice Reduces Methane Emissions by Limiting Acetic Acid Transport to the Rhizosphere and Inhibiting Methanogens

Advanced Science, EarlyView.
This study finds that the interaction between ABA‐OsCIPK2‐OsSWEET1A reduces the allocation of methane producing bacteria carbon source (acetic acid) content to the rhizosphere soil of ratoon season rice, thereby reducing methane emissions. Abstract Rice paddies are a major, persistent source of atmospheric methane (CH4), emission rates depend on the ...
Jingnan Zou, Hailong Xu, Bin Qin, Chaojie Lan, Jinying Li, Bianhong Zhang, Huabin Zhang, Chunlin Guo, Hongfei Chen, Zhongming Fang, Quanzhi Zhao, Wenfei Wang, Changxun Fang, Zhixing Zhang, Wenxiong Lin   +14 more
wiley   +1 more source

A Narrative Review of Human Papillomavirus (HPV) Vaccination in Ecuador: A Crisis of Inequity and an Evidence-Based Roadmap for Elimination. [PDF]

J Epidemiol Glob Health
Redrobán JDS, López D, Santillan C.
europepmc   +1 more source

A Novel Zinc(II) Complex for Sonodynamic Therapy Induces Pyroptosis of Breast Cancer Cells and Enhances Anti‐Tumor Immune Response

Advanced Science, EarlyView.
Although Zinc(II) complexes are effective in photodynamic therapy, their efficacy is limited by the poor tissue penetration of light. This work introduces a novel zinc(II) complex for sonodynamic therapy. Under ultrasound activation, it generates substantial singlet oxygen, induces pyroptosis in breast cancer cells, and promotes anti‐tumor immune ...
Sijie Wen, Dongsheng Tang, Lingpu Zhang, Hanchen Zhang, Zheng Cao, Kong Wai Tan, Xiaojun Wang, Haihua Xiao, Kun Shang   +8 more
wiley   +1 more source

Insufficient immune protection in preterm infants due to delayed or incomplete hexavalent vaccination. [PDF]

Front Immunol
Kaiser E, Weber R, Bous M, Fortmann I, Dammann MT, Marißen J, Viemann D, Derouet C, Hein S, Nourkami-Tutdibi N, Tutdibi E, Wuhrmann M, Hans MC, Gille C, Gehring S, Henneke P, Härtel C, Goedicke-Fritz S, Zemlin M.   +18 more
europepmc   +1 more source