Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre +12 more
wiley +1 more source
Reinstatement and a resurgence-like effect in an odor-signaled multiple schedule in rats. [PDF]
Mason MG +7 more
europepmc +1 more source
Attenuation of Influenza a Virus into Live Vaccines Through C‐End Degrons
Naturally occurring C‐end degrons are exploited to design proteolysis‐targeting live attenuated influenza vaccines. C‐end degron tagging of viral M1 protein promotes proteasome‐dependent degradation, resulting in robust attenuation in host cells while permitting scalable production in engineered cells.
Ping Wang +14 more
wiley +1 more source
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang +15 more
wiley +1 more source
Pneumococcal carriage among children and adults before and after a change from a three-dose 13-valent pneumococcal conjugate vaccine schedule without a booster to a two-dose schedule with a booster in Burkina Faso. [PDF]
Childs L +16 more
europepmc +1 more source
Incentive-Based Energy Consumption Scheduling Algorithms for the Smart Grid
Stéphane Caron, George Kesidis
openalex +2 more sources
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang +7 more
wiley +1 more source
Deep learning optimization of teaching schedules in sports dance education. [PDF]
Zhao G, Gu X, Du X, Yang Z.
europepmc +1 more source
p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa +23 more
wiley +1 more source
Planned synchronization for multi-robot systems with active observations. [PDF]
Zhong P, Rossi F, Shell DA.
europepmc +1 more source

