Results 31 to 40 of about 38,671 (260)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Hybrid Particle Swarm and Differential Evolution Algorithm for Solving Multimode Resource-Constrained Project Scheduling Problem

Journal of Control Science and Engineering, 2015
In order to find a feasible solution for the multimode resource-constrained project scheduling problem (MRCPSP), a hybrid of particle swarm optimization (PSO) and differential evolution (DE) algorithm is proposed in this paper.
Lieping Zhang, Yingxiong Luo, Yu Zhang
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Dynamic scheduling method for data relay satellite networks considering hybrid system disturbances

Complex & Intelligent Systems, 2023
System disturbances, such as the change of required service durations, the failure of resources, and temporary tasks during the scheduling process of data relay satellite network (DRSN), are difficult to be predicted, which may lead to unsuccessful ...
Zongling Li, Xinjiang Chen, Qizhang Luo, Guohua Wu, Ling Wang   +4 more
doaj   +1 more source

Dynamic MPC-Based Scheduling in a Smart Manufacturing System Problem

IEEE Access, 2023
This paper introduces a dynamic scheduling algorithm designed to minimize makespan within a smart manufacturing system, accommodating delays in the production process.
Alessandro Bozzi, Simone Graffione, Roberto Sacile, Enrico Zero   +3 more
doaj   +1 more source

Evaluation of a Broadcast Scheduling Algorithm [PDF]

, 2001
One of the two main approaches of data broadcasting is pull-based data delivery. In this paper, we focus on the problem of scheduling data items to broadcast in such a pull-based environment. Previous work has shown that the Longest Wait First heuristic has the best performance results compared to all other broadcast scheduling algorithms, however the ...
Murat Karakaya, Özgür Ulusoy
openaire   +3 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Start Time Planning for Cyclic Queuing and Forwarding in Time-Sensitive Networks

Mathematics
Time-sensitive networking (TSN) is a kind of network communication technology applied in fields such as industrial internet and intelligent transportation, capable of meeting the application requirements for precise time synchronization and low-latency ...
Daqian Liu, Zhewei Zhang, Yuntao Shi, Yingying Wang, Jingcheng Guo, Zhenwu Lei   +5 more
doaj   +1 more source

Hybrid Flow Shop Scheduling Problems Using Improved Fireworks Algorithm for Permutation

Applied Sciences, 2020
Prior studies are lacking which address permutation flow shop scheduling problems and hybrid flow shop scheduling problems together to help firms find the optimized scheduling strategy.
Xuelian Pang, Haoran Xue, Ming-Lang Tseng, Ming K. Lim, Kaihua Liu   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source