Results 191 to 200 of about 1,844,217 (391)
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
A New Framework for Job Shop Integrated Scheduling and Vehicle Path Planning Problem. [PDF]
Li R, Mao J, Wu X, Zhou W, Qian C, Du H.
europepmc +1 more source
A Method of Computer-Aided Process Planning for Machining Considering Production Scheduling
Nattapoom Charoenlarpkul +3 more
openalex +2 more sources
Evaluation of Production Process Scheduling in Order to Improve Optimization Using Genetic Algorithm
Ahmad Fikri Ardianto, Tedjo Sukmono
openalex +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Distributed Integrated Scheduling Algorithm for Identical Two-Workshop Based on the Improved Bipartite Graph. [PDF]
Wei Y, Zhou W, Zhao J, Tan Z, Xie Z.
europepmc +1 more source
Demand-side management via optimal production scheduling in power-intensive industries: The case of metal casting process [PDF]
Danial Ramin +2 more
openalex +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source

