Results 111 to 120 of about 737,834 (314)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The Relationship between Perceived Parenting Styles and Fear of Being Single: The Mediating Role of Dependency and Undeveloped Self Schemas [PDF]
The aim of the present study was to investigate the relationship between perceived parenting styles and the anxiety of being single, with dependency schemas and undeveloped self serving as mediators.
Mahtab Babaeian +2 more
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
bowtie-json-schema/bowtie: v0.80.0
What's Changed <ul> <li>Revamped the navbar added dropdown and support for mobile menu by @nomandhoni-cs in <a href="https://github.com/bowtie-json-schema/bowtie/pull/221">https://github.com/bowtie-json-schema/bowtie/pull/221</a> ...
Julian Berman +7 more
core +1 more source
Generalising the Z schema calculus: database schemas and beyond
The theory of relational databases has much in common with the mathematical structures central to the Z notation. Many authors have noted these connections in the past, but the development of the Z standard has provided a more natural way of making these links explicit.
Andrew P. Martin, Andrew Simpson 0001
openaire +3 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
bowtie-json-schema/bowtie: v0.54.0
What's Changed <ul> <li>Bump github.com/santhosh-tekuri/jsonschema/v5 from 5.1.0 to 5.1.1 in /implementations/go-jsonschema by @dependabot in <a href="https://github.com/bowtie-json-schema/bowtie/pull/91">https://github.com/bowtie-json ...
Julian Berman +3 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
bowtie-json-schema/bowtie: v2023.07.10
What's Changed <ul> <li>Update tutorial of bowtie documentation by @tcskiran in <a href="https://github.com/bowtie-json-schema/bowtie/pull/357">https://github.com/bowtie-json-schema/bowtie/pull/357</a></li> </ul> New ...
Julian Berman +10 more
core +1 more source

