Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong +10 more
wiley +1 more source
Research progress of schema therapy for adolescents. [PDF]
Zhang S, Zhang L.
europepmc +1 more source
Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan +7 more
wiley +1 more source
Psychological and Sociocultural Correlates of Genito-Pelvic Pain/Penetration Disorder in Iranian Women: A Comparative Study of Sexual Self-Schema and Temperament. [PDF]
Mohazzab A +8 more
europepmc +1 more source
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu +10 more
wiley +1 more source
The Relationship Between Early-Stage Maladaptive Schemas and Treatment Adherence in Patients Diagnosed with Bipolar Disorder in Remission. [PDF]
Karaytuğ MO +7 more
europepmc +1 more source
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang +13 more
wiley +1 more source
Schema Therapy for Children and Adolescents: A Systematic Review of Individual, Group, and Parent-Based Interventions. [PDF]
Uysal M +3 more
europepmc +1 more source
Accurate SPARQL generation via in-context learning and schema-based query construction. [PDF]
Nagazumi H +4 more
europepmc +1 more source
A next generation of the schema therapy model of personality pathology: A cross-cultural and international study protocol. [PDF]
Mamali FC +155 more
europepmc +1 more source

