Results 31 to 40 of about 648,597 (288)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Coupling Anodic Reactions in Electrochemical Nitrate Reduction to Ammonia

open access: yesChemElectroChem
Ammonia is a widely produced chemical globally, primarily used in fertilizers and chemical products. Recently, it has gained attention as a green hydrogen carrier due to its high hydrogen content and energy density.
Chaeeun Lim, Hyein Jo, Prof. Kijung Yong
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

A Model of Core Emotional Needs and Toxic Experiences: Their Links with Schema Domains, Well-Being, and Ill-Being

open access: yesBehavioral Sciences
This study examined the second-order schema domains of Early Maladaptive and Adaptive Schemas based on recent trends and compared them with the five theoretical second-order schema domains commonly used in schema therapy.
John Philip Louis   +2 more
doaj   +1 more source

Synthesizing Proximate and Distal Levels of Explanation: Toward an Evolution-Informed Sociology

open access: yesFrontiers in Sociology, 2018
In this paper, we argue that despite the growing acceptance of psychological research by mainstream sociologists, the discipline of sociology remains largely averse to biology.
Lawrence H. Williams   +1 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Semantics of Distinguishing Criteria: from Subjective to Intersubjective [PDF]

open access: yesInterdisciplinary Description of Complex Systems, 2012
In this article we are aiming to build cognitive semantics over a first person perspective. Our goal is to specify meanings connected to cognitive agents, rooted in their experience and separable from language, covering a wide spectrum of cognitions ...
Martin Takac, Jan Sefranek
doaj  

What Employees Do Today Because of Their Experience Yesterday: How Incidental Learning Influences Train Driver Behavior and Safety Margins (A Big Data Analysis)

open access: yesSafety, 2021
Employee behavior plays an important role in the occurrence and prevention of incidents, affecting safety margins. In this study, we examine the potential impact of incidental learning on human behavior in the presence of variation in task design ...
Julia Burggraaf   +3 more
doaj   +1 more source

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