Results 131 to 140 of about 71,535 (286)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Schema Evolution via Multi-Version Metadata in SaaS

, 2012
Shengqi Wu, Zhang Shidong, Lanju Kong
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

The logic of innovative value proposition: A schema for characterizing and predicting business model evolution

, 2019
Chester K.M. To, K.P. Chau, Chi Wai Kan
openalex   +2 more sources

Synchronization of Queries and Views Upon Schema Evolutions [PDF]

, 2016
Loredana Caruccio, Giuseppe Polese, Genoveffa Tortora   +2 more
openalex   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Schema Evolution and Versioning: A Logical and Computational Characterisation

, 2001
Enrico Franconi, Fábio Grandi, Federica Mandreoli   +2 more
openalex   +2 more sources

Managing Schema Evolution in NoSQL Data Stores [PDF]

, 2013
Stefanie Scherzinger, Meike Klettke, Uta Störl   +2 more
openalex   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

An Empirical Characterization of Event Sourced Systems and Their Schema Evolution - Lessons from Industry - Accompanying Anonymized Transcripts

, 2020
Michiel Overeem, Marten Spoor, Slinger Jansen, Sjaak Brinkkemper   +3 more
openalex   +2 more sources