Results 41 to 50 of about 253,331 (273)
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
A logic programming framework for modeling temporal objects [PDF]
, 1996 Published ...
Kesim, FN, Sergot, M
core +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Redai diliThe development of urbanization has fostered the rise of instrumental rationality and the decline of value rationality, leading to a diminishing sense of belonging among individuals in fast-paced urban life.
Liu Ruirui +4 more
doaj +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
ADEPT2 - Next Generation Process Management Technology [PDF]
, 2007 If current process management systems shall be applied to a broad spectrum of applications, they will have to be significantly improved with respect to their technological capabilities.
Acker, H. +7 more
core +2 more sources
Database queries and constraints via lifting problems
, 2013 Previous work has demonstrated that categories are useful and expressive models for databases. In the present paper we build on that model, showing that certain queries and constraints correspond to lifting problems, as found in modern approaches to ...
Barr +15 more
core +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
A CityGML extension for traffic-sign objects that guides the automatic processing of data collected using Mobile Mapping technology [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2014 The rapid evolution of integral schemes, accounting for geometric and semantic data, has been importantly motivated by the advances in the last decade in mobile laser scanning technology; automation in data processing has also recently influenced the ...
M. Varela-González +4 more
doaj +1 more source