Results 41 to 50 of about 656,169 (307)

XML-based genetic rules for scene boundary detection in a parallel processing environment [PDF]

, 2007
Genetic programming is based on Darwinian evolutionary theory that suggests that the best solution for a problem can be evolved by methods of natural selection of the fittest organisms in a population.
Angelides, MC, Parmar, MJ
core  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

PDGA: The primal-dual genetic algorithm [PDF]

, 2003
Copyright @ 2003 IOS PressGenetic algorithms (GAs) are a class of search algorithms based on principles of natural evolution. Hence, incorporating mechanisms used in nature may improve the performance of GAs.
Yang, S
core   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Representation Learning of Image Schema [PDF]

arXiv, 2022
Image schema is a recurrent pattern of reasoning where one entity is mapped into another. Image schema is similar to conceptual metaphor and is also related to metaphoric gesture. Our main goal is to generate metaphoric gestures for an Embodied Conversational Agent. We propose a technique to learn the vector representation of image schemas. As far as
arxiv  

Comprehensive clinical evaluation of novel 4DCT‐based lung function imaging methods

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Methods have been developed that apply image processing to 4DCTs to generate 4DCT‐ventilation/perfusion lung imaging. Traditional methods for 4DCT‐ventilation rely on Hounsfield‐Unit (HU) density‐change methods and suffer from poor numerical robustness while not providing 4DCT‐perfusion data.
Ehsan Golkar, Taindra Neupane, Lydia Wilson, Jennifer Kwak, Richard Castillo, Edward Castillo, Yevgeniy Vinogradskiy   +6 more
wiley   +1 more source

An investigation into the feasibility and efficacy of stereotactic radiosurgery for 1–3 cm single brain lesions on the ring‐mounted Halcyon LINAC

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose An evaluation of the accuracy, safety, and efficiency of the Halcyon ring delivery system (RDS) for stereotactic radiosurgery (SRS) treatment to relatively small (1–3 cm) brain lesions. Methods After completing the extensive in‐house quality assurance checks including Winston–Lutz test and independent dose verification via MD Anderson ...
Kate Hazelwood, Shane McCarthy, Josh Misa, David Castelvetere, William St. Clair, Damodar Pokhrel   +5 more
wiley   +1 more source

Adaptive group mutation for tackling deception in genetic search [PDF]

, 2004
Copyright @ 2004 WSEASIn order to study the efficacy of genetic algorithms (GAs), a number of fitness landscapes have been designed and used as test functions.
Yang, S
core  

A simple two-module problem to exemplify building-block assembly under crossover

, 2004
Theoretically and empirically it is clear that a genetic algorithm with crossover will outperform a genetic algorithm without crossover in some fitness landscapes, and vice versa in other landscapes.
D. Wolpert, D.E. Goldberg, G. Syswerda, H. Muhlenbein, J.C. Culberson, J.H. Holland, J.H. Holland, K. Deb, M. Mitchell, M. Mitchell, P. Gitchoff, P.F. Stadler, R.A. Fisher, R.A. Watson, R.A. Watson, S. Forrest, S. Forrest, S. Wright   +17 more
core   +2 more sources