Results 81 to 90 of about 134,507 (290)

MoPark Initiative, Metadata Options Appraisal (Phase I) [PDF]

open access: yes, 2004
Examines – and makes recommendations on - the needs of the Loch Lomond and Trossachs National Park as regards the metadata, metadata standards, and metadata management required for the competent handling of digital materials both now and in the future.
Nicholson, Dennis
core  

A framework for multi-tier type evolution and data migration [PDF]

open access: yes, 2004
This paper describes a framework that supports the simultaneous evolution of objectoriented data models and relational schemas with respect to a tool- supported object-relational mapping.
Draheim, Dirk   +2 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Towards a Holistic Integration of Spreadsheets with Databases: A Scalable Storage Engine for Presentational Data Management

open access: yes, 2017
Spreadsheet software is the tool of choice for interactive ad-hoc data management, with adoption by billions of users. However, spreadsheets are not scalable, unlike database systems.
Bendre, Mangesh   +4 more
core   +1 more source

Supporting Complex Scientific Database Schemas in a Grid Middleware [PDF]

open access: yes, 2009
“This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders.
Xiang, H.
core   +2 more sources

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

Transitioning Applications to Semantic Web Services: An Automated Formal Approach

open access: yes, 2008
Semantic Web Services have been recognized as a promising technology that exhibits huge commercial potential, and attract significant attention from both industry and the research community.
Gibbins, Nick   +4 more
core  

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

A Schema-Based DNA Algorithm Applicable on Graphics Processing Units

open access: yesIEEE Access, 2016
In this paper, an evolutionary algorithm inspired by biological deoxyribonucleic acid (DNA) computing is proposed to perform the task of optimization.
Kao-Shing Hwang   +2 more
doaj   +1 more source

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