Results 181 to 190 of about 2,151,357 (249)

BioBricks.ai: a versioned data registry for life sciences data assets. [PDF]

Front Artif Intell
Gao Y, Mughal Z, Jaramillo-Villegas JA, Corradi M, Borrel A, Lieberman B, Sharif S, Shaffer J, Fecho K, Chatrath A, Maertens A, Teunis MAT, Kleinstreuer N, Hartung T, Luechtefeld T.   +14 more
europepmc   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Updating MISEV: When, What, How, and Why? [PDF]

J Extracell Vesicles
Akbar N, Burger D, Bussolati B, Buzás EI, Carney RP, Cho YE, Driedonks TAP, Falcon-Perez JM, Fujita Y, Goberdhan DCI, Hendrix A, Huang Y, Mathivanan S, Mahoney MG, Mohanty S, Möller A, Noren Hooten N, Pluchino S, Salomon C, Torrecilhas AC, Veiga SI, Witwer KW.   +21 more
europepmc   +1 more source

Zwitterionic Polymer Coating Enabled Chronic Dopamine Sensing and Electrophysiology Recording in Free‐Moving Mice

Advanced Healthcare Materials, EarlyView.
Application of a zwitterionic poly(sulfobetaine methacrylate) (PSB) coating to microelectrode arrays and Ag/AgCl reference electrodes effectively inhibits biofouling and structural degradation. This strategy successfully enables simultaneous, long‐term electrophysiological recording and dopamine sensing in freely behaving mice, facilitating ...
Bingchen Wu, Cort Thompson, Thomas Deakin, Yan Xu, Colleen A. McClung, Xinyan Tracy Cui   +5 more
wiley   +1 more source

DNA Data Storage Architecture via Ligation of Dynamic DNA Bytes. [PDF]

Small Methods
Jia L, Shi Y, Yang J, Li S, Yang W, Li W, Zhang M, Li Q, Zhang Y, Wang X, Li L, Duan B, Bu D, Chen F, Liu H, Yang H, Shi Y, Liu D.   +17 more
europepmc   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

The Swiss Personalized Health Network Metadata Catalog: Platform for Health Data Discovery and Exploration Based on Findable, Accessible, Interoperable, and Reusable Principles. [PDF]

JMIR Med Inform
Witte H, Unni DR, Krauss P, Touré V, Armida J, Österle S.   +5 more
europepmc   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Challenging the status quo: A guide to open and reproducible neuroimaging for early career researchers. [PDF]

Imaging Neurosci (Camb)
Bhagwat N, Urchs S, Poline JB, Yang YF.
europepmc   +1 more source