Results 21 to 30 of about 2,151,357 (249)

Efficient Management of Schema Versioning in Multi-Temporal Databases. [PDF]

Int. Arab J. Inf. Technol., 2012
To guarantee a complete data history in temporal databases, database management systems have to manage both evolution of schema over time, through their versioning, and evolution of data defined under different schema versions. This paper proposes a new approach for schema versioning in multi-temporal databases.
Brahmia, Zouhaier, Mkaouar, Mohamed, Chakhar, Salem, Bouaziz, Rafik   +3 more
openaire   +3 more sources

Reconciling Versioning and Context in Hypermedia Structure Servers

, 2002
Contextual structure servers and versioning servers share a similar goal in allowing different views on a stored structure according to the viewer’s perspective. In this paper we argue that a generic contextual model can be used to facilitate versioning.
Griffiths, Jon, Davis, Hugh, Michaelides, Danius T., Weal, Mark J., Millard, David E.   +4 more
core   +2 more sources

Consistency check between XML schema and class diagram for document versioning [PDF]

, 2018
A consistency check between design and implementation is usually done in order to check the correctness of the system’ requirements. However, if the requirements are changed over time, then the document versioning occurred within the requirements.
Nayak, Richi, Jamel, Sapiee, Aman, Hannani, Ibrahim, Rosziati   +3 more
core   +4 more sources

Ai–Blockchain-Enabled Halal Traceability for Cross-Border Certification Harmonization: A Framework for Digital Halal Assurance

Lan Tabur
This study addresses the increasing complexity of cross-border halal trade, where fragmented certification regimes and differing regulatory and fiqh-based approaches raise verification costs and weaken trust.
Ita Marianingsih, Salim Salim, Sadiq Ibrahim Mijinyawa   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Toward a Domain-Overarching Metadata Schema for Making Health Research Studies FAIR (Findable, Accessible, Interoperable, and Reusable): Development of the NFDI4Health Metadata Schema

JMIR Medical Informatics
BackgroundDespite wide acceptance in medical research, implementation of the FAIR (findability, accessibility, interoperability, and reusability) principles in certain health domains and interoperability across data sources remain
Haitham Abaza, Aliaksandra Shutsko, Sophie A I Klopfenstein, Carina N Vorisek, Carsten Oliver Schmidt, Claudia Brünings-Kuppe, Vera Clemens, Johannes Darms, Sabine Hanß, Timm Intemann, Franziska Jannasch, Elisa Kasbohm, Birte Lindstädt, Matthias Löbe, Katharina Nimptsch, Ute Nöthlings, Marisabel Gonzalez Ocanto, Tracy Bonsu Osei, Ines Perrar, Manuela Peters, Tobias Pischon, Ulrich Sax, Matthias B Schulze, Florian Schwarz, Carolina Schwedhelm, Sylvia Thun, Dagmar Waltemath, Hannes Wünsche, Atinkut A Zeleke, Wolfgang Müller, Martin Golebiewski   +30 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source