Results 41 to 50 of about 583,328 (263)

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

On a Finite Differnce Scheme For Blow Up Solutions For The Chipot-Weissler Equation [PDF]

open access: yes, 2015
In this paper, we are interested in the numerical analysis of blow up for the Chipot-Weissler equation with Dirichlet boundary conditions in bounded domain.
Hani, Houda, Khenissi, Moez
core  

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

open access: yesFEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Blind signature scheme based on entangled quantum

open access: yesTongxin xuebao, 2016
Based on the principle of quantum entanglement swapping, a blind signature scheme based on quantum entanglement was proposed.Through being entangled and exchanged, particles prepared before could transform into entangled state.
Jian-wu LIANG   +3 more
doaj   +2 more sources

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

open access: yesFEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado   +4 more
wiley   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

Nonlinear Operators as Concerns Convex Programming and Applied to Signal Processing

open access: yesMathematics, 2019
Splitting methods have received a lot of attention lately because many nonlinear problems that arise in the areas used, such as signal processing and image restoration, are modeled in mathematics as a nonlinear equation, and this operator is decomposed ...
Anantachai Padcharoen   +1 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

APOS Theory in Learning Mathematics (Using Trigonometry as an Example)

open access: yesИнтеграция образования
Introduction. One of the most well-known theories that allows us to study the process of structuring a concept in the mind of a student is the APOS theory, specially created for the study of mental processes in mathematical education and worthy of ...
Nail K. Tuktamyshov   +1 more
doaj   +1 more source

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