Results 91 to 100 of about 50,344 (211)

Cytotoxic and Antileishmanial Potential of Pilocarpus microphyllus Essential Oil: In Vitro and In Silico Study

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
Jaborandi (Pilocarpus microphyllus) essential oil is obtained by removal and characterization using GC‐MS, revealing γ‐cadinene and trans‐caryophyllene as major constituents. The oil exhibits biological activity, with antifungal action against Candida spp.
Juniel Cruz Silva, Maria Gabriela Araújo Mendes, Paulo Sérgio de Araujo Sousa, Alyne Rodrigues de Araújo Nobre, Michel Muálem de Moraes Alves, Fernando Aécio de Amorim Carvalho, Tatiane Caroline Daboit, José de Sousa Lima Neto, Ygor Victor Ferreira Pinheiro, Ytallo da Costa Sousa, Edymilaís da Silva Sousa, José Delano Barreto Marinho Filho, Ana Jérsia Araújo, Francisco Artur Silva Filho, Sidney Gonçalo de Lima, Leiz Maria Costa Véras   +15 more
wiley   +1 more source

Prevalence and factors associated with Schistosoma mansoni infection among primary school children in Kersa District, Eastern Ethiopia [PDF]

PeerJ
Background Schistosomiasis is a neglected tropical disease and an important parasite negatively impacting socio-economic factors. Ethiopia’s Federal Ministry of Health targeted the elimination of schistosomiasis infection in school-aged children by 2020.
Hussen Aliyi, Mohammed Ahmed, Tesfaye Gobena, Bezatu Mengistie Alemu, Hassen Abdi Adem, Ahmedin Aliyi Usso   +5 more
doaj   +2 more sources

Helminths in the gastrointestinal tract 1 as modulators of immunity and pathology [PDF]

, 2017
Helminth parasites are highly prevalent in many low- and middle-income countries, in which inflammatory bowel disease and other immunopathologies are less frequent than in the developed world.
Fleming, John O., Maizels, Richard, Varyani, Fumi   +2 more
core   +1 more source

9‐Deoxymuzigadial, a Sesquiterpene Isolated From Drimys brasiliensis (Winteraceae), Displays Reduced Cytotoxicity In Vitro and Modulates Leukocyte Activity and Fibrogenesis In Vivo

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The aims of this study were to investigate in vitro cytotoxic potential and the effects of daily administration during the inflammatory response induced by sponge implants in mice of the sesquiterpene 9‐deoxymuzigadial (9‐DOM), isolated from Drimys brasiliensis (Winteraceae).
Bruno Antonio Ferreira, Isabella Silva Cassimiro, Francyelle Borges Rosa de Moura, Tais de Campos Lima, Danielle Reis Napolitano, Eric Umehara, João Henrique Ghilardi Lago, Fernanda de Assis Araújo   +7 more
wiley   +1 more source

Biochemical, coagulation, and platelet count profiles among Schistosoma mansoni infected patients attending at selected Dembiya health institutions, Northwest Ethiopia

BMC Microbiology
Background Schistosomiasis is a parasitic disease that causes coagulation disorders and biochemical abnormalities. This is due to liver failure, platelet destruction, disruption of blood flow, and endothelial function by the schistosomes.
Wagaw Abebe, Wossenseged Lemma, Yalewayker Tegegne, Assefa Sisay, Tadesse Misganaw, Sisay Ayana, Desie Kasew, Marye Nigatie Debash, Alemu Birara Zemariam, Tadele Emagneneh, Adane Derso   +10 more
doaj   +1 more source

Schistosomal peritonitis secondary to perforated appendicitis

Brazilian Journal of Infectious Diseases, 2010
In Tanzania, Schistosoma mansoni is endemic and causes intestinal schistosomiasis which affects various internal organs. However, worldwide there have been very few reports of cases of peritonitis due to schistosomal appendicitis.
Humphrey D. Mazigo, Geofrey C. Giiti, Maria Zinga, Jorg Heukelbach, Peter Rambau   +4 more
doaj   +1 more source

Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. [PDF]

, 2006
Immunophilin is the collective name given to the cyclophilin and FK506-binding protein (FKBP) families. As the name suggests, these include the major binding proteins of certain immunosuppressive drugs: cyclophilins for the cyclic peptide cyclosporin A ...
Adams, Aliberti, Alphey, Angus Bell, Antony P. Page, Argaet, Banerjee, Banumathy, Belfiore, Bell, Bell, Bell, Berriman, Blumenthal, Blumenthal, Borel, Bozdech, Braun, Bua, Carlton, Chakraborty, Chakraborty, Chappell, Chappell, Cianciotto, Cohen, Colgan, Dao-Thi, Denkers, Dobson, Dolinski, Dornan, Dornan, Dutta, Fischer, Florens, Galat, Galat, Gavigan, Gavigan, Gilleard, Golding, Hacker, Hall, High, Hirtzlin, Hong, Hope, Kamath, Kay, Ke, Khattab, Kiang, Klinkert, Klinkert, Knobloch, Kumar, Kumar, Kumar, Le Roch, Lightowlers, Lorberg, Ma, Ma, Ma, Matsuda, McLauchlan, Mikol, Monaghan, Monaghan, Moro, Osman, Ostoa-Saloma, Oz, Page, Page, Page, Page, Page, Page, Page, Paul Monaghan, Pelle, Pereira, Peterson, Picken, Pratt, Rascher, Reddy, Riggs, Rossi, Shirane, Silverman, Taylor, Tuo, Valle, Wang, Weiwad, Williams, Yarovinsky, Yu, Zorio   +101 more
core   +1 more source

Experimental schistosomiasis in the Common Marmoset Callithrix jacchus

Revista da Sociedade Brasileira de Medicina Tropical, 2004
In order to evaluate Callithrix jacchus as an animal model for mansoni schistosomiasis, a group of 10 male animals were once percutaneously exposed to 250 cercariae of the Schistosoma mansoni SLM (São Lourenço da Mata) strain.
Ana Luna de Oliveira, Elizabeth Malagueño, Adriana Maria da Silva Telles, Maria Helena Madruga, José Valfrido de Santana   +4 more
doaj  

Schistosome serine protease inhibitors: parasite defense or homeostasis?

Anais da Academia Brasileira de Ciências, 2011
Serpins are a structurally conserved family of macromolecular inhibitors found in numerous biological systems. The completion and annotation of the genomes of Schistosoma mansoni and Schistosoma japonicum has enabled the identification by phylogenetic ...
Landys A. Lopez Quezada, James H McKerrow   +1 more
doaj   +1 more source

New approaches to measuring anthelminthic drug efficacy: parasitological responses of childhood schistosome infections to treatment with praziquantel [PDF]

, 2015
By 2020, the global health community aims to control and eliminate human helminthiases, including schistosomiasis in selected African countries, principally by preventive chemotherapy (PCT) through mass drug administration (MDA) of anthelminthics ...
A Danso-Appiah, A Fenwick, A Montresor, A Vidyashankar, AC Gelman, AE Butterworth, AL Bustinduy, Alexandra U. Scherrer, AU Scherrer, B Levecke, BM Bolker, CH King, Charles H. King, CJL Murray, CL Black, D Alonso, D Bates, F Thiongo, G Raso, Giovanna Raso, GR Olds, IM Silva, J Cabaret, J Modha, J Smith, J Utzinger, J Utzinger, J Utzinger, J. Russell Stothard, JA Hanley, JC Sousa-Figueiredo, JD Hadfield, Jean T. Coulibaly, José Carlos Sousa-Figueiredo, JP Webster, JT Coulibaly, Jürg Utzinger, K Stete, Katarina Stete, M Albonico, M Booth, M Ismail, M Nielsen, M Reddy, M Walker, Maria-Gloria Basáñez, Martin Walker, ME Mejía, MEJ Woolhouse, MG Basáñez, MJ Bockarie, MJ Doenhoff, MJ Doenhoff, P Andrews, P Fallon, PH Lamberton, Piero L. Olliaro, PJ Brindley, PJ Diggle, PJ Hotez, PL Olliaro, PNM Mwinzi, R Core Team, S Anayi, SD Melman, SJ Vlas de, SN Lahiri, SV Subramanian, Tarub S. Mabud, TW Jia, U Halekoh, W Harnett, W Wang, World Health Organization, World Health Organization, World Health Organization   +75 more
core   +4 more sources