Results 61 to 70 of about 58,567 (180)

Development of new lateral-flow immunochromatographic strip using colloidal gold and mesoporous silica nanoparticles for rapid diagnosis of active schistosomiasis

Asian Pacific Journal of Tropical Biomedicine, 2019
Objective: To develop a new sandwich based lateral flow immunochromatographic strip for rapid detection of circulating Schistosoma mansoni antigen in serum and urine samples of patients with active schistosomiasis.
Manal Kamel, Faten Salah, Zeinab Demerdash, Sara Maher, Shimaa Atta, Abeer Badr, Ahmed Afifi, Hanan El Baz   +7 more
doaj   +1 more source

Reduced Efficacy of Praziquantel Against Schistosoma mansoni Is Associated With Multiple Rounds of Mass Drug Administration

Clinical Infectious Diseases, 2016
The efficacy of praziquantel against Schistosoma mansoni was significantly lower in Ugandan schools that had received more prior rounds of mass drug administration, as determined by fitting a statistical model to parasite egg counts before and after ...
Thomas Crellen, M. Walker, P. Lamberton, N. Kabatereine, E. Tukahebwa, J. Cotton, J. Webster   +6 more
semanticscholar   +1 more source

A Whole‐Genome Investigation of Mitonuclear Discordance in the Trematode Parasite Atriophallophorus winterbourni

Molecular Ecology, Volume 35, Issue 10, May 2026.
ABSTRACT Faster evolution of mitochondrial genomes relative to nuclear genomes creates selective pressure on nuclear genes involved in mitochondrial function to preserve mitonuclear compatibility required for energy production. In isolated populations, such coevolution occurs independently.
Natalia Zajac, Frida Feijen, Jukka Jokela   +2 more
wiley   +1 more source

Under diagnosis of intestinal schistosomiasis in a referral hospital, North Ethiopia

BMC Research Notes, 2018
Objective The present cross-sectional study was aimed at determining the magnitude of under diagnosis of intestinal schistosomiasis among patients requested for routine ova/parasite examination at Ayder referral hospital.
Megbaru Alemu, Eyob Zigta, Awoke Derbie
doaj   +1 more source

Current Status of Schistosomiasis in Egypt: Parasitologic and Endoscopic Study in Sharqia Governorate [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases, 2011
Background and study aim: Schistosomiasis was endemic in Egypt since the ancient times. It was traditionally the most important public health problem.
Mohamed Refaey, Walid Abdel-Dayem, Mona El-Motyam, Hossam Salah, Amany Ibrahim, Mohielddin Abdul-Fattah, Tarik Zaher   +6 more
doaj   +1 more source

Whole genome resequencing of the human parasite Schistosoma mansoni reveals population history and effects of selection

Scientific Reports, 2016
Schistosoma mansoni is a parasitic fluke that infects millions of people in the developing world. This study presents the first application of population genomics to S.
Thomas Crellen, F. Allan, S. David, C. Durrant, Thomas Huckvale, Nancy E. Holroyd, A. Emery, D. Rollinson, D. Aanensen, M. Berriman, J. Webster, J. Cotton   +11 more
semanticscholar   +1 more source

Fair and Square: Design, Synthesis and Biological Evaluations of Squaric Acid Derivatives as Novel HDAC8 Inhibitors

ChemMedChem, Volume 21, Issue 8, 28 April 2026.
Histone deacetylase 8 (HDAC8) is a clinically validated target in neuroblastoma, where isoform selective inhibition offers a strategy to suppress tumour growth while limiting off‐target toxicity. Hydroxamic acids remain the dominant zinc‐binding group (ZBG) in HDAC inhibitors but are also associated with metabolic instability, suboptimal ...
Nathan Long, Franz‐Josef Meyer‐Almes, Aleksandra Kopranovic, Stephen P. Wren   +3 more
wiley   +1 more source

Parasitological and clinical correlates of Plasmodium–Schistosoma mansoni co-infection and its determinants among Plasmodium-infected patients in the Wolaita Zone, South Ethiopia regional state

Frontiers in Malaria
BackgroundMalaria and schistosomiasis are among the most important parasitic diseases with overlapping geographical distribution in Ethiopia. The objective of this study, therefore, was to assess parasitological and clinical correlates and determinants ...
Kemal Mohamed, Tariku Belay, Ahmed Zeynudin   +2 more
doaj   +1 more source

Seleção genética de Biomphalaria glabrata e Biomphalaria tenagophila visando a alteração da suscetibilidade e resistência ao Schistosoma mansoni Genetic selection of Biomphalaria glabrata and Biomphalaria tenagophila seeking the alteration of the susceptibility and resistance to the Schistosoma mansoni

Revista da Sociedade Brasileira de Medicina Tropical, 2005
Gerações de Biomphalaria glabrata e Biomphalaria tenagophila selecionadas geneticamente para resistência e suscetibilidade ao Schistosoma mansoni das linhagens BH e SJ foram utilizadas no estudo da adaptação do trematódeo ao hospedeiro intermediário.
Nádia Regina Borim Zuim, Eliana Maria Zanotti-Magalhães, Luiz Augusto Magalhães, Arício Xavier Linhares   +3 more
doaj   +1 more source

Prevalence and Predictors Associated to Schistosoma mansoni Infection among Patients Attending the Saint Jean de Malte Hospital, Njombe, Littoral Region, Cameroon

Journal of Parasitology Research, 2023
Background. Schistosomiasis remains a major public health concern in sub-Saharan Africa. It has been associated to morbidity and mortality in developing countries including Cameroon, and Njombe-Penja health district is an endemic area.
Ambe Fabrice Ngwa, Pride Tanyi Bobga, Ekwi Damian Nsongmayi, Gedeon Schadrack Yememe Yememe, Judith Ngong Nyeme, Mohamed Isah, Ebai Christabel Ashu, Calvin Bisong Ebai   +7 more
doaj   +1 more source