Results 91 to 100 of about 42,766 (225)

Laboratory diagnosis of schistosomiasis mansoni: Current status and future trends

Asian Pacific Journal of Tropical Medicine, 2019
Schistosomiasis is a neglected tropical disease that affects about 290 million patients worldwide. Children aged between 5 and 14 years represent 45.8% of the affected patients, in addition, schistosomiasis has been reported in Schistosoma-free areas ...
Amira Taman, Samar N El-Beshbishi
doaj   +1 more source

Efficacy and safety of moxidectin, synriam, synriam-praziquantel versus praziquantel against schistosoma haematobium and S. mansoni infections: a randomized, exploratory phase 2 trial [PDF]

, 2016
Schistosomiasis affects millions of people, yet treatment options are limited. The antimalarial Synriam (piperaquine 150 mg/arterolane 750 mg) and the anthelminthic moxidectin revealed promising antischistosomal properties in preclinical or clinical ...
Puchkov, Maxim, Maxim Puchkov, Jennifer Keiser, Jörg Huwyler, Coulibaly, Jean T., Beatrice Barda (717878), Maxim Puchkov (3123930), Jean T Coulibaly, Jan Hattendorf (113923), Jörg Huwyler (166572), Beatrice Barda, Jean T. Coulibaly (108845), Huwyler, Jörg, Hattendorf, Jan, Keiser, Jennifer, Jennifer Keiser (39606), Barda, Beatrice, Jan Hattendorf   +17 more
core   +2 more sources

Characterization of Transcriptional, Epigenetic, and Phenotypic Plasticity and Discovery of Biomarkers in Acute and Chronic Murine Schistosomiasis Infection

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Workflow for discovering parasitological and molecular changes related to Schistosoma mansoni infection. ABSTRACT Parasites can induce changes in their hosts, favoring the success of the infection and its development at each stage of their life cycle.
Sheila de Andrade Penteado Corrêa, Cauã da Silva Oliveira Teodoro, João Paulo Luz da Silva, Fabio Queiroz, Tayná Dandara do Amaral, Silmara Marques Allegretti, Fernanda Silva de Oliveira, Rafaela Ferraz Teixeira, Lizandra Maia de Sousa, Sílvio Roberto Consonni, Matheus de Souza Gomes, Christoph Grunau, Fernanda Janku Cabral   +12 more
wiley   +1 more source

Praziquantel analogs with activity against juvenile Schistosoma mansoni.

, 2010
Six amide and four urea derivatives of praziquantel were synthesized and tested for antischistosomal activity against juvenile and adults stages of Schistosoma mansoni in infected mice. Only one of these had significant activity against adult worms, but,
Vennerstrom, Jonathan L, Bickle, Quentin, Bickle, Q., Chollet, Jacques, Keiser, J., Mansour, N. R., Alnouti, Yazen, Huang, Jiangeng, Vennerstrom, J. L., Mansour, Nuha R, Dong, Y., Keiser, Jennifer, Vargas, M., Dong, Yuxiang, Alnouti, Y., Vargas, Mireille, Chollet, J., Huang, J.   +17 more
core   +1 more source

An in-depth analysis of a piece of shit : distribution of Schistosoma mansoni and hookworm eggs in human stool [PDF]

, 2012
BACKGROUND: An accurate diagnosis of helminth infection is important to improve patient management. However, there is considerable intra- and inter-specimen variation of helminth egg counts in human feces.
N'Goran Eliézer K., N'Goran, E. K., Krauth, Stefanie J., Knopp, S., Utzinger, Jürg, Coulibaly, Jean T., Jean T Coulibaly, Stefanie Knopp, Traoré, M., Utzinger Jürg, Jean T. Coulibaly (108845), Coulibaly Jean T., Jürg Utzinger, Krauth, S. J., Krauth Stefanie J., Stefanie J Krauth, Coulibaly, J. T., Eliézer K. N'Goran (108853), Utzinger, J., Jürg Utzinger (39609), Stefanie Knopp (108848), Stefanie J. Krauth (108843), Traoré Mahamadou, Eliézer K N'Goran, Traoré, Mahamadou, N'Goran, Eliézer, Mahamadou Traoré (108851), Knopp, Stefanie, Knopp Stefanie, Mahamadou Traoré   +29 more
core   +1 more source

Extracellular Vesicle Properties and Functions Are Defined by the Originating Cell's Fitness Status

Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.
ABSTRACT Recent studies have focused on the role of dying cells in modulating immune function and shaping the local microenvironment. Apoptotic cells release various extracellular vesicles (EVs), such as exosomes and microvesicles, and form apoptotic bodies through membrane blebbing.
Stephanie Leyk, Imke Liebold, Clarissa Lanzloth, Ulricke Richardt, Johan M. Kux, Christoph Kilian, Manuela Moritz, Antonia Gocke, Simon Meyer, Katharina Höhn, Barbara Honecker, Helmut Haas, Marius Böttcher, Sören Weidemann, Simon Kind, Hartmut Schlüter, Nahla Galal Metwally, Lorenz Adlung, Pablo J. Sáez, Thomas Jacobs, Klaus Ruckdeschel, Lidia Bosurgi   +21 more
wiley   +1 more source

Tools to support policy decisions related to treatment strategies and surveillance of Schistosomiasis japonica towards elimination. [PDF]

, 2011
BACKGROUND: Appropriate diagnostics to monitor disease trends and assess the effectiveness and impact of interventions are essential for guiding treatment strategies at different thresholds of schistosomiasis transmission and for certifying elimination ...
Lin, Dan-Dan, Tang, Li, Lin Dan-Dan, Li, Hao, Chen, Hong-Gen, Wang Qi-Zhi, Guo Jia-Gang, Wu Xiao-Hua, Guo, Jian, Jing Xu, Guo, Jia-Gang, Guo Jian, Xiao-Hua Wu, Xiao-Nong Zhou, Jia-Gang Guo, Chen Hong-Gen, Zhou, Xiao-Nong, Chen Shao-Hong, Peeling Rosanna W., Feng, Ting, Wang Tian-Ping, Chen Jia-Xu, Xu, Jing, Chen, Jia-Xu, Huang Xi-Bao, Wang, Tian-Ping, Tang Li, Wu Zhong-Dao, Tian-Ping Wang, Dan-Dan Lin, Peeling, Rosanna W, Wu, Zhong-Dao, Jia-Xu Chen, Xu Jing, Ting Feng, Li Tang, Chen, Shao-Hong, Hao Li, Jian Guo, Wu, Xiao-Hua, Zhou Xiao-Nong, Hong-Gen Chen, Wang, Qi-Zhi, Qi-Zhi Wang, Li Hao, Xi-Bao Huang, Huang, Xi-Bao, Rosanna W Peeling, Shao-Hong Chen, Zhong-Dao Wu, Feng Ting   +50 more
core   +2 more sources

Crystal structure of Schistosoma mansoni cathepsin D1 in complex with a nanobody reveals the conformation of the propeptide‐bound state

Acta Crystallographica Section D, Volume 82, Issue 2, Page 140-150, February 2026.
Structural characterization of S. mansoni cathepsin D1 in complex with a nanobody reveals the conformation of the propeptide‐bound state and identifies a schistosome‐specific epitope.Schistosoma mansoni cathepsin D1 (SmCD1) has been shown to be an essential enzyme for helminth metabolism due to its role in haemoglobin degradation: a key amino‐acid ...
Kelly L. Parker, John D. Clarke, Xiaojiao Liu, Barbara F. Gomes, Lauren E.-A. Eyssen, Nicholas Furnham, Floriano Paes Silva-Jr, Raymond J. Owens   +7 more
wiley   +1 more source

Genital schistosomiasis mansoni concomitant to genital tumor in areas of low endemicity: challenging diagnosis

Brazilian Journal of Infectious Diseases, 2011
Genital infection by Schistosoma mansoni is usually misdiagnosed in individuals who reside in, or travel to endemic areas. We describe two cases of genital tumor associated with S. mansoni infection manifested by methrorragy.
Marta G. Cavalcanti, Margareth M.I. Gonçalves, Magali M. Barreto, Aline Helen da Silva, Kalil Madi, José Mauro Peralta, Ricardo P. Igreja   +6 more
doaj   +1 more source

Between Droughts and Floods: The Seasonal Response of Freshwater Snails in Artificial Reservoirs in the Brazilian Semiarid Region

Population Ecology, Volume 68, Issue 1, January 2026.
We investigate the seasonal dynamics of two freshwater snails, Biomphalaria straminea and Melanoides tuberculata, in artificial reservoirs of the Brazilian semiarid region. Despite regulated hydrology, B. straminea exhibited strong seasonal fluctuations associated with dry periods, while M. tuberculata maintained stable populations throughout the year,
Lucas Henrique Sousa da Silva, João Hemerson de Sousa, Adriana Josefa da Rocha, Manuella Feitosa Leal, Lucas Ariel de Sousa Aguiar, Tamaris Gimenez Pinheiro, Edson Lourenço da Silva   +6 more
wiley   +1 more source