Results 61 to 70 of about 28,245 (262)

A loop-mediated isothermal amplification (LAMP) assay for early detection of Schistosoma mansoni in stool samples: a diagnostic approach in a murine model. [PDF]

PLoS Neglected Tropical Diseases, 2014
Human schistosomiasis, mainly due to Schistosoma mansoni species, is one of the most prevalent parasitic diseases worldwide. To overcome the drawbacks of classical parasitological and serological methods in detecting S.
Pedro Fernández-Soto, Javier Gandasegui Arahuetes, Alicia Sánchez Hernández, Julio López Abán, Belén Vicente Santiago, Antonio Muro   +5 more
doaj   +1 more source

Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas [PDF]

, 2015
Background: Point-of-care (POC) tests for diagnosing schistosomiasis include tests based on circulating antigen detection and urine reagent strip tests.
Bossuyt, P.M.M., Gopalakrishna, G., Lamberton, P., Leeflang, M.M.G., Ochodo, E.A., Polman, K., Reitsma, J.B., Spek, B., van Lieshout, L.   +8 more
core   +3 more sources

Characterization of Transcriptional, Epigenetic, and Phenotypic Plasticity and Discovery of Biomarkers in Acute and Chronic Murine Schistosomiasis Infection

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Workflow for discovering parasitological and molecular changes related to Schistosoma mansoni infection. ABSTRACT Parasites can induce changes in their hosts, favoring the success of the infection and its development at each stage of their life cycle.
Sheila de Andrade Penteado Corrêa, Cauã da Silva Oliveira Teodoro, João Paulo Luz da Silva, Fabio Queiroz, Tayná Dandara do Amaral, Silmara Marques Allegretti, Fernanda Silva de Oliveira, Rafaela Ferraz Teixeira, Lizandra Maia de Sousa, Sílvio Roberto Consonni, Matheus de Souza Gomes, Christoph Grunau, Fernanda Janku Cabral   +12 more
wiley   +1 more source

CD4+ T cell hyporesponsiveness after repeated exposure to Schistosoma mansoni larvae is dependent upon interleukin-10 [PDF]

, 2015
The effect that multiple percutaneous exposures to Schistosoma larvae has on the development of early CD4+ lymphocyte reactivity is unclear, yet it is important in the context of humans living in areas where schistosomiasis is endemic.
Cook, Peter C., Mountford, Adrian P., Prendergast, Catriona T., Sanin, David E.   +3 more
core   +1 more source

Extracellular Vesicle Properties and Functions Are Defined by the Originating Cell's Fitness Status

Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.
ABSTRACT Recent studies have focused on the role of dying cells in modulating immune function and shaping the local microenvironment. Apoptotic cells release various extracellular vesicles (EVs), such as exosomes and microvesicles, and form apoptotic bodies through membrane blebbing.
Stephanie Leyk, Imke Liebold, Clarissa Lanzloth, Ulricke Richardt, Johan M. Kux, Christoph Kilian, Manuela Moritz, Antonia Gocke, Simon Meyer, Katharina Höhn, Barbara Honecker, Helmut Haas, Marius Böttcher, Sören Weidemann, Simon Kind, Hartmut Schlüter, Nahla Galal Metwally, Lorenz Adlung, Pablo J. Sáez, Thomas Jacobs, Klaus Ruckdeschel, Lidia Bosurgi   +21 more
wiley   +1 more source

The effect of anthelmintic treatment during pregnancy on HIV plasma viral load: results from a randomized, double-blind, placebo-controlled trial in Uganda. [PDF]

, 2012
BACKGROUND: To investigate the effect of helminth infections and their treatment during pregnancy on HIV load, we conducted a 2 × 2 factorial randomized controlled trial of albendazole versus placebo and praziquantel versus placebo in pregnant women in ...
Elliott, Alison M, Kaleebu, Pontiano, Kizito, Dennison, Kyosiimire-Lugemwa, Jacqueline, Lule, Swaib, Muhangi, Lawrence, Muwanga, Moses, Nkurunziza, Peter, Webb, Emily L   +8 more
core   +1 more source

Crystal structure of Schistosoma mansoni cathepsin D1 in complex with a nanobody reveals the conformation of the propeptide‐bound state

Acta Crystallographica Section D, Volume 82, Issue 2, Page 140-150, February 2026.
Structural characterization of S. mansoni cathepsin D1 in complex with a nanobody reveals the conformation of the propeptide‐bound state and identifies a schistosome‐specific epitope.Schistosoma mansoni cathepsin D1 (SmCD1) has been shown to be an essential enzyme for helminth metabolism due to its role in haemoglobin degradation: a key amino‐acid ...
Kelly L. Parker, John D. Clarke, Xiaojiao Liu, Barbara F. Gomes, Lauren E.-A. Eyssen, Nicholas Furnham, Floriano Paes Silva-Jr, Raymond J. Owens   +7 more
wiley   +1 more source

Development, validation, and pilot application of a high throughput molecular xenomonitoring assay to detect Schistosoma mansoni and other trematode species within Biomphalaria freshwater snail hosts

Current Research in Parasitology and Vector-Borne Diseases
Schistosomiasis is a neglected tropical disease (NTD) caused by infection with parasitic trematodes of the genus Schistosoma that can lead to debilitating morbidity and mortality.
John Archer, Shi Min Yeo, Grace Gadd, Tom Pennance, Lucas J. Cunningham, Alexandra Juhàsz, Sam Jones, Priscilla Chammudzi, Donales R. Kapira, David Lally, Gladys Namacha, Bright Mainga, Peter Makaula, James E. LaCourse, Sekeleghe A. Kayuni, Janelisa Musaya, J. Russell Stothard, Bonnie L. Webster   +17 more
doaj   +1 more source

One Health – an Ecological and Evolutionary Framework for tackling Neglected Zoonotic Diseases [PDF]

, 2015
Understanding the complex population biology and transmission ecology of multihost parasites has been declared as one of the major challenges of biomedical sciences for the 21st century and the Neglected Zoonotic Diseases (NZDs) are perhaps the most ...
Adamo, Akopyants, Anderson, Antia, Azevedo, Berry, Betson, Biswas, Boatin, Boissier, Chargui, Civetello, Cleaveland, Combes, Consortium* THG, Crichton, Criscione, Cutillas, Delgado, Detwiler, Dobson, Doby, Dunams-Morel, Eberhard, Fan, Faye, Fenton, Fenton, Fraga de Azevedo, Funk, Garba, Gaunt, Gelanew, Genis, Gibbs, Gibson, Gouvras, Gretillat, Grigg, Gupta, Hahn, Hahn, Hanelt, Hargrove, Haydon, Hotez, Hotez, Huyse, Huyse, Inpankaew, Johnson, Jolles, Kaushik, Kaushik, Keesing, Kelly, Kilpatrick, King, Klepac, Koukounari, Lamberton, Laval, Le, Leger, Lembo, Liang, Liese, Lloyd-Smith, Lu, Lu, Lu, Lu, Lustigman, Machado, Maia, Mathews, Mavarez, Messenger, Messenger, Miles, Molyneux, Moné, Muhanguzi, Muller-Graf, Mupfasoni, Norton, Pardo-Diaz, Parrish, Pedersen, Perez-Quintero, Ramiro, Randolph, Ravel, Robinson, Rogers, Rollinson, Rudge, Rudge, Rudge, Salkeld, Saroufim, Silva Oliveira, Smith, Steinauer, Strauss, Streicker, Streicker, Sturm, Taylor, Theron, Theron, Tomley, UNDP, Viana, Volf, Wang, Webby, Webster, Webster, Webster, Webster, Webster, Webster, Welburn, Welburn, Whitlock, WHO, Wood, Woolhouse, Woolhouse, Woolhouse, Woolhouse, Woolhouse, Yamane, Yamane, Zhou   +135 more
core   +4 more sources

Between Droughts and Floods: The Seasonal Response of Freshwater Snails in Artificial Reservoirs in the Brazilian Semiarid Region

Population Ecology, Volume 68, Issue 1, January 2026.
We investigate the seasonal dynamics of two freshwater snails, Biomphalaria straminea and Melanoides tuberculata, in artificial reservoirs of the Brazilian semiarid region. Despite regulated hydrology, B. straminea exhibited strong seasonal fluctuations associated with dry periods, while M. tuberculata maintained stable populations throughout the year,
Lucas Henrique Sousa da Silva, João Hemerson de Sousa, Adriana Josefa da Rocha, Manuella Feitosa Leal, Lucas Ariel de Sousa Aguiar, Tamaris Gimenez Pinheiro, Edson Lourenço da Silva   +6 more
wiley   +1 more source