Results 61 to 70 of about 42,766 (225)

Synthesis and Antiparasitic Activities of New Organometallic Derivatives of the Benzimidazole Anthelmintic Drugs

ChemBioChem, Volume 27, Issue 15, 14 August 2026.
Organometallic derivatization of existing drugs is a common strategy to look for new drug candidates. This work describes the derivatization of the benzimidazole anthelmintic scaffold, from the synthesis of the organometallic derivatives to the evaluation of their biological properties. It highlights a broad range of antiparasitic activities and leaves
Corentin Ludwig, Aya C. Taki, Joseph J. Byrne, Pierre Mesdom, Olivier Blacque, Cécile Häberli, Trix Zumkehr, Gonzalo Scalese, Leticia Pérez‐Díaz, Dinorah Gambino, Britta Lundström‐Stadelmann, Jennifer Keiser, Robin B. Gasser, Kevin Cariou, Gilles Gasser   +14 more
wiley   +1 more source

Schistosomiasis transmission in Zimbabwe: Modelling based on machine learning

Infectious Disease Modelling
Zimbabwe, located in Southern Africa, faces a significant public health challenge due to schistosomiasis. We investigated this issue with emphasis on risk prediction of schistosomiasis for the entire population. To this end, we reviewed available data on
Hong-Mei Li, Jin-Xin Zheng, Nicholas Midzi, Masceline Jenipher Mutsaka- Makuvaza, Shan Lv, Shang Xia, Ying-jun Qian, Ning Xiao, Robert Berguist, Xiao-Nong Zhou   +9 more
doaj   +1 more source

Gaining and sustaining schistosomiasis control : study protocol and baseline data prior to different treatment strategies in five African countries [PDF]

, 2016
The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) was established in 2008 to answer strategic questions about schistosomiasis control.
W. Evan Secor, Eliézer K. N’Goran, Utzinger, Jürg, King, Charles H., Magnussen, Pascal, Secor, W. Evan, Ferro, J, Daniel G. Colley, N'Goran, EK, Carl H. Campbell, Xiao-Ping Yin, Shen, Y, Christopher C. Whalen, Kinung'hi, Safari, Ye Shen, Ezeamama, Amara E., Garba, Amadou, Utzinger, J, Hamidou, A, Rathbun, S, Fenwick, A, Mwinzi, Pauline N. M., Colley, DG, Anna Phillips, Whalen, Christopher C., Diana M. S. Karanja, Olsen, A, Charles H. King, Montgomery, S, Phillips, Anna, Campbell, Carl H., Amadou Garba, Garba, A, Kinung'hi, S, Fenwick, Alan, Ezeamama, AE, Susan Montgomery, Colley, Daniel G., Secor, WE, He, C-L, Stephen Rathbun, Alan Fenwick, Campbell, CH, King, CH, Pascal Magnussen, Yin, X-P, Olsen, Annette, Ferro, Josefo, Sue C. Binder, Pauline N. M. Mwinzi, Magnussen, P, Karanja, Diana M. S., Amara E. Ezeamama, Chun-La He, Mwinzi, PNM, Jürg Utzinger, Annette Olsen, Binder, Sue C., Josefo Ferro, He, Chun-La, Safari Kinung’hi, Montgomery, Susan, Whalen, CC, Amina Hamidou, Binder, SC, Rathbun, Stephen, Hamidou, Amina, N'Goran, Eliézer K., Phillips, A, Shen, Ye, Karanja, DMS, Yin, Xiao-Ping   +71 more
core   +1 more source

No Simple Fluke: Schistosomiasis as an Emerging Regulator of Haematopoiesis

Parasite Immunology, Volume 48, Issue 7, July 2026.
ABSTRACT Schistosomiasis, or bilharzia, is a highly prevalent water‐borne helminth infection that accounts for an estimated 1.5–1.7 billion disability‐adjusted life years lost annually. Pathology driven by adult worms and eggs is accompanied by robust immunomodulation in the human host. Protective responses may promote worm elimination, limit bystander
Shinjini Chakraborty
wiley   +1 more source

Treatment of Schistosomiasis mansoni with Neostibosan.

Experimental Biology and Medicine, 1946
Twelve patients with ova of 5. mansoni in their stools were treated with the pentavalent antimonial drug, neostibosan (Winthrop). The patients were all males with ages ranging from 15 to 32 years. The drug was administered intravenously during a 2-week period of hospitalization.
F, HERNANDEZ-MORALES, J, OLIVER-GONZALEZ, C K, PRATT   +2 more
openaire   +2 more sources

Intestinal Parasitic Infections and Associated Factors Among Psychiatric Patients at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Intestinal parasitic infections pose significant public health challenges in developing countries. They are major concerns in rehabilitation centers for individuals with mental disabilities. However, little attention has been given to preventing these infections among the mentally disabled groups.
Andargachew Almaw, Bekele Sharew, Shewaneh Damtie, Tegenaw Tiruneh, Aynework Abebaw, Birhanemaskal Malkamu, Dessie Tegegne, Birhanu Getie, Mulat Erkihun, Ayenew Assefa, Getu Abeje, Teklehaimanot Kiros, Sinedu Moges, Kirubel Shiferaw, Mengistu Tesfa Alula, Mihreteab Alebachew, Birhanu Malede, Ayenew Berhan   +17 more
wiley   +1 more source

Development of an in vitro drug screening assay using Schistosoma haematobium schistosomula [PDF]

, 2012
BACKGROUND: The development of novel antischistosomal drugs is crucial, as currently no vaccine and only a single drug is available for the treatment of schistosomiasis.
Ingram, K., Katrin Ingram, Marxer Monika, Marxer, Monika, Jennifer Keiser, Ingram Katrin, Keiser Jennifer, Keiser, Jennifer, Marxer, M., Keiser, J., Monika Marxer, Ingram, Katrin   +11 more
core   +1 more source

Nonlinear Imaging Allows to Characterize Granulomas and Fibrosis in Mice Tissue From Experimental Schistosomiasis

Journal of Biophotonics, Volume 19, Issue 6, June 2026.
Second Harmonic Generation and Two‐Photon Excitation Fluorescence microscopy allows to characterize mice tissues infected with Schistosoma mansoni in an experimental model. ABSTRACT Schistosomiasis is a neglected disease caused by parasites of the genus Schistosoma that poses serious public health problems.
Gladystone Rocha da Fonseca, Rennan R. M. Lima, Ronald Eduardo Soares, Bárbara Regina Melo Ribeiro, Paulo E. Cabral Filho, Adriana Fontes, Ana Maria de Paula   +6 more
wiley   +1 more source

Altered purinergic P2X7 and A2B receptors signaling limits macrophage-mediated host defense in schistosomiasis

Biomedical Journal
Background: The occurrence of co-infections during schistosomiasis, a neglected tropical disease, with other parasites have been reported suggesting an impaired host immune defense.
Maria Luiza Thorstenberg, Monique Daiane Andrade Martins, Nathália Ferreira Oliveira, Matheus Macedo L.V. Monteiro, Gustavo R.C. Santos, Henrique M. Gualberto Pereira, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva, Claudia Lucia Martins Silva   +8 more
doaj   +1 more source

A loop-mediated isothermal amplification (LAMP) assay for early detection of Schistosoma mansoni in stool samples: a diagnostic approach in a murine model. [PDF]

PLoS Neglected Tropical Diseases, 2014
Human schistosomiasis, mainly due to Schistosoma mansoni species, is one of the most prevalent parasitic diseases worldwide. To overcome the drawbacks of classical parasitological and serological methods in detecting S.
Pedro Fernández-Soto, Javier Gandasegui Arahuetes, Alicia Sánchez Hernández, Julio López Abán, Belén Vicente Santiago, Antonio Muro   +5 more
doaj   +1 more source