Abnormal negative feedback processing in first episode schizophrenia: evidence from an oculomotor rule switching task [PDF]
Background. Previous studies have shown that patients with schizophrenia are impaired on executive tasks, where positive and negative feedbacks are used to update task rules or switch attention.
Andreasen+8 more
core +1 more source
Schizophrenia is a TH2 dominant autoimmune disease possibly against acetylcholine receptors of CNS [PDF]
Schizophrenia is a very common psychiatric disorder. However, its etiology and pathogenesis is still unknown. Current theory saying that neurotransmitter imbalance such as serotonin or dopamine only provides limited effectiveness in schizophrenia ...
Wanchung(Wan-Jiung) Hu
core +1 more source
Subanesthetic ketamine treatment promotes abnormal interactions between neural subsystems and alters the properties of functional brain networks [PDF]
Acute treatment with subanesthetic ketamine, a non-competitive N-methyl-D-aspartic acid (NMDA) receptor antagonist, is widely utilized as a translational model for schizophrenia. However, how acute NMDA receptor blockade impacts on brain functioning at a
A Bifone+77 more
core +1 more source
BackgroundPsychotic disorders are characterized by white matter (WM) abnormalities; however, their relationship with the various aspects of illness presentation remains unclear.
Umit Haluk Yesilkaya+13 more
doaj +1 more source
What does a mouse tell us about neuregulin 1 – cannabis interactions?
The link between cannabis and psychosis has been debated although there is substantial epidemiological evidence showing that cannabis increases the risk of psychosis.
Tim eKarl+5 more
doaj +1 more source
Many who pick up this book will be learning about schizophrenia for the first time, either because someone they care about has recently been diagnosed, or purely out of academic interest.
J. S. Strauss+3 more
semanticscholar +1 more source
Prevalence & Prescription: Prescribing Practices of Clozapine in Australia between 2005 & 2010 [PDF]
Clozapine is an anti-psychotic used to treat refractory schizophrenia. This study reviews the rates of clozapine prescription for refractory schizophrenia in a region of Australia and compares the prescribing patterns to the estimated prevalence rates of
Pai, NB, Vella, SC
core +2 more sources
Pdxdc1 modulates prepulse inhibition of acoustic startle in the mouse. [PDF]
Current antipsychotic medications used to treat schizophrenia all target the dopamine D2 receptor. Although these drugs have serious side effects and limited efficacy, no novel molecular targets for schizophrenia treatment have been successfully ...
Boutros, PC+5 more
core +1 more source
Correction to: Skating on thin ice: pragmatic prescribing for medication refractory schizophrenia
After publication of the original article [1], the authors have notified us that there was an oversight on acknowledging funding received for the study. They would like to mention that Professor Sukhi Shergill was funded by an ERC Consolidator Award.
Derek K. Tracy+4 more
doaj +1 more source
Global economic burden of schizophrenia: a systematic review
Background Schizophrenia is one of the top 25 leading causes of disability worldwide in 2013. Despite its low prevalence, its health, social, and economic burden has been tremendous, not only for patients but also for families, caregivers, and the wider ...
H. Chong+5 more
semanticscholar +1 more source