Results 121 to 130 of about 1,025,722 (378)
No Effects of Cognitive Remediation on Cerebral White Matter in Individuals at Ultra-High Risk for Psychosis—A Randomized Clinical Trial
Frontiers in Psychiatry, 2020 BackgroundIndividuals at ultra-high risk for psychosis (UHR) present with subtle alterations in cerebral white matter (WM), which appear to be associated with clinical and functional outcome.Tina D. Kristensen, Tina D. Kristensen, Bjørn H. Ebdrup, Bjørn H. Ebdrup, Bjørn H. Ebdrup, Carsten Hjorthøj, Carsten Hjorthøj, René C. W. Mandl, René C. W. Mandl, Jayachandra M. Raghava, Jayachandra M. Raghava, Jens Richardt M. Jepsen, Jens Richardt M. Jepsen, Birgitte Fagerlund, Birgitte Fagerlund, Louise B. Glenthøj, Louise B. Glenthøj, Christina Wenneberg, Christina Wenneberg, Kristine Krakauer, Christos Pantelis, Christos Pantelis, Birte Y. Glenthøj, Birte Y. Glenthøj, Merete Nordentoft, Merete Nordentoft, Merete Nordentoft +26 moredoaj +1 more sourceMapping genomic loci implicates genes and synaptic biology in schizophrenia
Nature, 2022 V. Trubetskoy, A. Pardiñas, Ting Qi, Georgia Panagiotaropoulou, S. Awasthi, T. Bigdeli, J. Bryois, Chia-Yen Chen, Charlotte A Dennison, L. Hall, Max W. Y. Lam, Kyoko Watanabe, O. Frei, T. Ge, J. Harwood, F. Koopmans, S. Magnússon, A. Richards, J. Sidorenko, Yang Wu, Jian Zeng, J. Grove, Minsoo Kim, Zhiqiang Li, G. Voloudakis, Wen Zhang, M. Adams, I. Agartz, Elizabeth G. Atkinson, E. Agerbo, M. A. Al Eissa, M. Albus, Madeline Alexander, B. Alizadeh, K. Alptekin, T. Als, F. Amin, V. Arolt, M. Arrojo, L. Athanasiu, M. Azevedo, S. Bacanu, N. Bass, M. Begemann, R. Belliveau, J. Bene, Beben Benyamin, Sarah E. Bergen, G. Blasi, J. Bobes, S. Bonassi, A. Braun, R. Bressan, E. Bromet, R. Bruggeman, P. Buckley, R. Buckner, J. Bybjerg-Grauholm, W. Cahn, M. Cairns, M. Calkins, V. Carr, D. Castle, S. Catts, K. Chambert, R. Chan, B. Chaumette, Wei Cheng, E. Cheung, S. Chong, D. Cohen, A. Consoli, Q. Cordeiro, J. Costas, C. Curtis, M. Davidson, K. Davis, L. de Haan, F. Degenhardt, L. DeLisi, D. Demontis, F. Dickerson, D. Dikeos, T. Dinan, S. Djurovic, J. Duan, G. Ducci, F. Dudbridge, J. Eriksson, L. Fañanás, S. Faraone, A. Fiorentino, A. Forstner, J. Frank, N. Freimer, M. Fromer, A. Frustaci, A. Gadelha, G. Genovese, E. Gershon, M. Giannitelli, I. Giegling, P. Giusti-Rodríguez, S. Godard, J. Goldstein, Javier González Peñas, A. González-Pinto, S. Gopal, J. Gratten, Michael F. Green, T. Greenwood, O. Guillin, Sinan Gülöksüz, R. Gur, R. Gur, B. Gutiérrez, E. Hahn, H. Hakonarson, V. Haroutunian, A. Hartmann, C. Harvey, C. Hayward, F. Henskens, S. Herms, P. Hoffmann, D. Howrigan, M. Ikeda, C. Iyegbe, I. Joa, A. Julià, A. Kähler, T. Kam-Thong, Y. Kamatani, Sena Karachanak-Yankova, O. Kebir, M. Keller, B. Kelly, A. Khrunin, Sung-Wan Kim, J. Kloviņš, N. Kondratiev, B. Konte, J. Kraft, M. Kubo, V. Kučinskas, Z. Kučinskienė, A. Kusumawardhani, Hana Kuzelova-Ptackova, S. Landi, L. Lazzeroni, Phil H. Lee, S. Legge, D. Lehrer, R. Lencer, B. Lerer, Miaoxin Li, J. Lieberman, G. Light, S. Limborska, Chih-Min Liu, J. Lönnqvist, C. Loughland, J. Lubiński, J. Luykx, A. Lynham, M. Macek, Andrew Mackinnon, P. Magnusson, B. Maher, W. Maier, D. Malaspina, J. Mallet, S. Marder, S. Marsal, Alicia R. Martin, L. Martorell, M. Mattheisen, R. McCarley, C. Mcdonald, J. Mcgrath, H. Medeiros, S. Meier, B. Melegh, I. Melle, R. Mesholam-Gately, A. Metspalu, P. Michie, L. Milani, V. Milanova, M. Mitjans, E. Molden, E. Molina, M. Moltó, V. Mondelli, C. Moreno, C. Morley, G. Muntané, K. Murphy, I. Myin‐Germeys, I. Nenadić, G. Nestadt, L. Nikitina-Zake, Cristiano Noto, K. Nuechterlein, N. O’Brien, F. O’Neill, Sang-Yun Oh, A. Olincy, V. Ota, C. Pantelis, G. Papadimitriou, M. Parellada, T. Paunio, R. Pellegrino, S. Periyasamy, D. Perkins, B. Pfuhlmann, O. Pietiläinen, J. Pimm, D. Porteous, J. Powell, D. Quattrone, D. Quested, A. Radant, A. Rampino, M. Rapaport, A. Rautanen, A. Reichenberg, Cheryl A. Roe, J. Roffman, Julian Roth, M. Rothermundt, B. Rutten, Safa Saker-Delye, V. Salomaa, J. Sanjuán, M. Santoro, A. Savitz, U. Schall, Rodney J. Scott, L. Seidman, S. Sharp, Jianxin Shi, L. Siever, E. Sigurdsson, K. Sim, Nora Skarabis, P. Slominsky, H. So, J. Sobell, E. Söderman, H. Stain, N. Steen, Agnes A. Steixner-Kumar, Elisabeth Stögmann, W. Stone, R. Straub, F. Streit, E. Strengman, T. Stroup, M. Subramaniam, Catherine A. Sugar, J. Suvisaari, D. Svrakic, N. Swerdlow, J. Szatkiewicz, T. Ta, A. Takahashi, C. Terao, F. Thibaut, D. Toncheva, P. Tooney, Silvia Torretta, S. Tosato, G. Tura, B. Turetsky, A. Üçok, A. Vaaler, T. van Amelsvoort, R. van Winkel, J. Veijola, J. Waddington, H. Walter, A. Waterreus, B. Webb, M. Weiser, N. Williams, S. Witt, B. Wormley, J. Wu, Zhida Xu, R. Yolken, C. Zai, Wei Zhou, Feng Zhu, F. Zimprich, E. Atbasoglu, M. Ayub, C. Benner, A. Bertolino, D. Black, N. Bray, G. Breen, N. Buccola, W. Byerley, Wei J. Chen, C. Cloninger, B. Crespo-Facorro, G. Donohoe, R. Freedman, C. Galletly, M. Gandal, M. Gennarelli, D. Hougaard, H. Hwu, A. Jablensky, S. Mccarroll, J. Moran, O. Mors, P. Mortensen, B. Müller-Myhsok, A. Neil, M. Nordentoft, M. Pato, T. Petryshen, M. Pirinen, A. Pulver, T. Schulze, J. Silverman, J. Smoller, E. Stahl, D. Tsuang, E. Vilella, Shi-Heng Wang, Shuhua Xu, R. Adolfsson, C. Arango, B. Baune, S. Belangero, A. Børglum, D. Braff, E. Bramon, J. Buxbaum, D. Campion, J. Cervilla, S. Cichon, D. A. Collier, A. Corvin, D. Curtis, M. Forti, E. Domenici, H. Ehrenreich, V. Escott-Price, T. Esko, A. Fanous, A. Gareeva, M. Gawlik, P. Gejman, M. Gill, S. Glatt, V. Golimbet, K. Hong, C. Hultman, S. Hyman, N. Iwata, E. Jönsson, R. Kahn, James L. Kennedy, E. Khusnutdinova, G. Kirov, J. Knowles, M. Krebs, C. Laurent-Levinson, Jimmy Lee, T. Lencz, D. Levinson, Qingqin S. Li, J. Liu, A. Malhotra, D. Malhotra, A. McIntosh, A. McQuillin, P. Menezes, V. Morgan, D. Morris, B. Mowry, Robin M. Murray, V. Nimgaonkar, M. Nöthen, R. Ophoff, S. Paciga, A. Palotie, C. Pato, Shengying Qin, M. Rietschel, B. Riley, M. Rivera, D. Rujescu, M. C. Saka, A. Sanders, S. Schwab, A. Serretti, P. Sham, Yongyong Shi, D. St. Clair, H. Stefánsson, K. Stefánsson, M. Tsuang, J. van os, M. Vawter, D. Weinberger, T. Werge, D. Wildenauer, Xin Yu, W. Yue, P. Holmans, A. Pocklington, P. Roussos, E. Vassos, M. Verhage, P. Visscher, Jian Yang, D. Posthuma, O. Andreassen, K. Kendler, M. Owen, N. Wray, M. Daly, Hailiang Huang, B. Neale, Patrick F. Sullivan, S. Ripke, J. Walters, M. O’Donovan +433 moresemanticscholar +1 more sourceBioprinted Organoids: An Innovative Engine in Biomedicine
Advanced Science, EarlyView.Bioprinted organoids refer to either the printing of stem cells into tissue shape and subsequent differentiate into organoids, or assembling induced organoids as bioinks to replicate native organ. It enables the creation of miniaturized organs with complex architectures and physiological functions, potentially enhancing reproducibility, throughput, and Zhengwei Li, Kai Li, Cheng Zhang, Yingying Zhao, Yiyuan Guo, Jia He, Shiyuan Chang, Xinyi Fang, Kaizheng Liu, Pingping Zhu, Zhenzhen Chen, Changshun Ruan +11 morewiley +1 more sourceProtein Spatial Structure Meets Artificial Intelligence: Revolutionizing Drug Synergy–Antagonism in Precision Medicine
Advanced Science, EarlyView.This review comprehensively examines the applications of protein three‐dimensional structures and artificial intelligence in investigating drug synergistic and antagonistic effects. The research findings provide compelling evidence for the precision treatment of cancer and metabolic diseases, thereby promoting the development of personalized medicine ...Anqi Lin, Chang Che, Aimin Jiang, Chang Qi, Antonino Glaviano, Zhijie Zhao, Zhirou Zhang, Zaoqu Liu, Ziyao Zhou, Quan Cheng, Shuofeng Yuan, Peng Luo +11 morewiley +1 more sourceNeural response to specific components of fearful faces in healthy and schizophrenic adults [PDF]
, 2009 Perception of fearful faces is associated with functional activation of cortico-limbic structures, which has been found altered in individuals with psychiatric disorders such as schizophrenia, autism and major depression.Brammer, Michael J., David, Anthony S., El-Hage, Wissam, Giampietro, Vincent, Kalidindi, Sridevi, Lawrence, Natalia, Marshall, Nicolette, McDonald, Colm, Phillips, Mary L., Radua, Joaquim, Russell, Tamara, Surguladze, Simon A. +11 morecore +1 more sourceWidespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group
Molecular Psychiatry, 2017 The regional distribution of white matter (WM) abnormalities in schizophrenia remains poorly understood, and reported disease effects on the brain vary widely between studies.S. Kelly, N. Jahanshad, A. Zalesky, P. Kochunov, I. Agartz, C. Alloza, O. Andreassen, C. Arango, N. Banaj, S. Bouix, C. Bousman, R. Brouwer, J. Bruggemann, J. Bustillo, W. Cahn, V. Calhoun, D. Cannon, V. Carr, S. Catts, J. Chen, J.X. Chen, X. Chen, C. Chiapponi, K. K. Cho, V. Ciullo, A. Corvin, B. Crespo-Facorro, V. Cropley, P. de Rossi, C. Díaz-Caneja, E. Dickie, S. Ehrlich, F. Fan, Joshua Faskowitz, H. Fatouros-Bergman, L. Flyckt, J. Ford, J. Fouche, M. Fukunaga, M. Gill, D. Glahn, R. Gollub, E. Goudzwaard, H. Guo, R. Gur, R. Gur, T. Gurholt, R. Hashimoto, S. Hatton, F. Henskens, D. Hibar, I. Hickie, L. Hong, J. Horáček, F. Howells, H. H. Hulshoff Pol, C. Hyde, D. Isaev, A. Jablensky, P. Jansen, J. Janssen, E. Jönsson, L. Jung, R. Kahn, Z. Kikinis, K. Liu, P. Klauser, C. Knöchel, M. Kubicki, J. Lagopoulos, C. Langen, S. Lawrie, R. Lenroot, K. Lim, C. López-Jaramillo, A. Lyall, V. Magnotta, R. Mandl, D. Mathalon, R. McCarley, S. McCarthy-Jones, C. Mcdonald, S. McEwen, A. McIntosh, T. Melicher, R. Mesholam-Gately, P. Michie, B. Mowry, B. Mueller, D. Newell, P. O’Donnell, V. Oertel-Knöchel, L. Oestreich, S. Paciga, C. Pantelis, O. Pasternak, G. Pearlson, G. Pellicanò, A. Pereira, J. P. Pineda Zapata, F. Piras, S. Potkin, Adrian Preda, P. Rasser, D. Roalf, R. Roiz, A. Roos, D. Rotenberg, T. Satterthwaite, P. Savadjiev, U. Schall, R. Scott, M. Seal, L. Seidman, C. Shannon Weickert, C. Whelan, M. Shenton, J. Kwon, G. Spalletta, F. Španiel, E. Sprooten, M. Stäblein, Dan J Stein, S. Sundram, Y. Tan, S. Tan, S. Tang, H. Temmingh, L. Westlye, S. Tønnesen, D. Tordesillas-Gutiérrez, N. T. Doan, J. Vaidya, N. V. van Haren, C. Vargas, D. Vecchio, D. Velakoulis, A. Voineskos, J. Voyvodic, Z. Wang, P. Wan, D. Wei, T. Weickert, H. Whalley, T. White, T. Whitford, J. Wojcik, H. Xiang, Z. Xie, H. Yamamori, F. Yang, N. Yao, G. Zhang, J. Zhao, T. V. van Erp, J. Turner, P. Thompson, G. Donohoe +157 moresemanticscholar +1 more sourceAnalyses of GWAS and Sub‐Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic Risk
Advanced Science, EarlyView.A cost‐effective strategy is developed analyzing sub‐threshold GWAS loci (5 × 10−8 < P ≤ 10−6), identifying 180 risk loci and 304 high‐confidence genes through combined GWAS/subGWAS analysis. This approach reveals dendrite development and morphogenesis (DDM) as a novel SCZ pathway.Rui Chen, Benjamin Siciliano, Quan Wang, Chongchong Xu, Qiang Wei, Hai Yang, James S Sutcliffe, Yi Jiang, Ying Ji, Chunyu Liu, Feixiong Cheng, Edwin H Cook, Nancy J Cox, Xue Zhong, Zhexing Wen, Bingshan Li +15 morewiley +1 more source
