Results 121 to 130 of about 1,069,369 (339)

Poor self-reported sleep is associated with prolonged white matter T2 relaxation in psychotic disorders

open access: yesFrontiers in Psychiatry
BackgroundPsychotic disorders are characterized by white matter (WM) abnormalities; however, their relationship with the various aspects of illness presentation remains unclear.
Umit Haluk Yesilkaya   +13 more
doaj   +1 more source

Current Concepts and Treatments of Schizophrenia

open access: yesMolecules, 2018
Schizophrenia is a debilitating mental illness which involves three groups of symptoms, i.e., positive, negative and cognitive, and has major public health implications. According to various sources, it affects up to 1% of the population.
Piotr Stępnicki   +2 more
semanticscholar   +1 more source

Neurodevelopmental and Psychiatric Studies in Children and Adolescents With Neurofibromatosis Type I: A Comprehensive Scoping Review

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT A comprehensive synthesis of the broad range of neurodevelopmental and psychiatric manifestations in NF1 is needed to identify knowledge gaps and future directions for NF1 research. In the following scoping review, we identify and summarize the scope of research that examines neurodevelopmental and psychiatric manifestations, both as ...
Meera Chopra   +5 more
wiley   +1 more source

Attenuated mismatch negativity in patients with first-episode antipsychotic-naive schizophrenia using a source-resolved method

open access: yesNeuroImage: Clinical, 2019
Background: Mismatch negativity (MMN) is a measure of pre-attentive auditory information processing related to change detection. Traditional scalp-level EEG methods consistently find attenuated MMN in patients with chronic but not first-episode ...
M. Randau   +6 more
doaj   +1 more source

Are There Causal Associations Between Obsessive‐Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi‐Directional Mendelian Randomization Study

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT In epidemiological studies, obsessive‐compulsive disorder (OCD) is robustly associated with increased risk of cardiometabolic disorders, including cardiovascular diseases, type 2 diabetes, and obesity. However, the mechanisms behind these associations are unclear. We conducted genetic correlation analyses to explore shared genetic etiology and
Robyn E. Wootton   +217 more
wiley   +1 more source

Cerebral blood flow autoregulation is impaired in schizophrenia [PDF]

open access: yes, 2017
Patients with schizophrenia have a higher risk of cardiovascular diseases and higher mortality from them than does the general population; however, the underlying mechanism remains unclear.
al, et, Ku, Hsiao-Lun, Lane, Timothy
core  

Multimorbidity and animal models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang   +7 more
wiley   +1 more source

Traumatic Experiences, Psychological Distress and Suicide‐Related Behaviors in Autistic Adults

open access: yesAutism Research, EarlyView.
ABSTRACT Autistic adults have increased risks of trauma, suicide, and poor mental health compared to non‐autistic adults, with 1 in 4 autistic adults attempting suicide. We administered an anonymized, self‐report survey to 424 autistic and 345 non‐autistic adults through a convenience sampling framework.
T. A. Chikaura   +9 more
wiley   +1 more source

Ethical Issues in Delivering Psychological Therapies in Geriatric Psychiatry in India

open access: yesIndian Journal of Psychological Medicine, 2021
Sridhar Vaitheswaran   +7 more
doaj   +1 more source

Feasibility Study of a Novel App‐Based Anxiety Intervention for Autistic People

open access: yesAutism Research, EarlyView.
ABSTRACT At least 50% of autistic people experience clinically relevant anxiety symptoms. However, reasons for elevated rates of anxiety in autism remain poorly understood and there is a high unmet need for novel and adapted therapies for anxiety that are accessible to autistic people.
Bethany Oakley   +18 more
wiley   +1 more source

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