Temperature affects the biology of Schmidtea mediterranea. [PDF]
Sci Rep, 2018 AbstractStudies of tissue regeneration and host-pathogen interactions using the model planarian Schmidtea mediterranea have been performed at an experimental temperature of 19 °C. S. mediterranea planarians exposed to 19 °C–32 °C were observed for survival, mobility, feeding and regeneration for three months and elimination of the Staphylococcus aureus
Hammoudi N +3 more
europepmc +5 more sources
Schmidtea mediterranea as a Model Organism to Study the Molecular Background of Human Motile Ciliopathies. [PDF]
Int J Mol Sci, 2023 Cilia and flagella are evolutionarily conserved organelles that form protrusions on the surface of many growth-arrested or differentiated eukaryotic cells.
Rabiasz A, Ziętkiewicz E.
europepmc +2 more sources
Cell type transcriptome atlas for the planarian Schmidtea mediterranea. [PDF]
Science, 2018 Mapping the planarian transcriptome A cell type's transcriptome defines the active genes that control its biology. Two groups used single-cell RNA sequencing to define the transcriptomes for essentially all cell types of a complete animal, the regenerative planarian Schmidtea mediterranea.
Fincher CT +4 more
europepmc +5 more sources
Comprehensive RNA-Seq Analysis Pipeline for Non-Model Organisms and Its Application in Schmidtea mediterranea. [PDF]
Genes (Basel), 2023 RNA sequencing (RNA-seq) is a high-throughput technology that provides in-depth information on transcriptome. The advancement and dropping costs of RNA sequencing, accompanied by more available reference genomes for different species, make transcriptome ...
Wang Y +6 more
europepmc +2 more sources
Whole-Mount In Situ Hybridization in Large Sexual Schmidtea mediterranea.
Methods in molecular biology, 2023 Whole-mount in situ hybridization (WISH), colorimetric or fluorescent (FISH), allows for the visualization of endogenous RNA. For planarians, robust WISH protocols exist for small-sized animals (>5 mm) of the model species Schmidtea mediterranea and Dugesia japonica.
Miquel Vila‐Farré +2 more
semanticscholar +6 more sources
Molecular markers to characterize the hermaphroditic reproductive system of the planarian Schmidtea mediterranea [PDF]
, 2011 Background The freshwater planarian Schmidtea mediterranea exhibits two distinct reproductive modes. Individuals of the sexual strain are cross-fertilizing hermaphrodites with reproductive organs that develop post-embryonically.
Tracy Chong +3 more
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The repertoire of G protein-coupled receptors in the human parasite Schistosoma mansoni and the model organism Schmidtea mediterranea [PDF]
, 2011 Background G protein-coupled receptors (GPCRs) constitute one of the largest groupings of eukaryotic proteins, and represent a particularly lucrative set of pharmaceutical targets.
Mostafa Zamanian +5 more
openalex +5 more sources
Transcriptome Analysis Reveals Strain-Specific and Conserved Stemness Genes in Schmidtea mediterranea [PDF]
PLoS ONE, 2012 The planarian Schmidtea mediterranea is a powerful model organism for studying stem cell biology due to its extraordinary regenerative ability mediated by neoblasts, a population of adult somatic stem cells. Elucidation of the S.
Dasaradhi Palakodeti +2 more
exaly +2 more sources
Knockdown of armc3 Impairs Motile Cilia Function in Schmidtea mediterranea [PDF]
MicroPubl BiolCilia are microtubule-based structures lining epithelial surfaces of many organs and play an essential role in diverse metabolic and developmental processes. Structural or functional disruptions of cilia can lead to ciliopathies affecting multiple organs.
Gogoi C +4 more
europepmc +2 more sources
Smed454 dataset: unravelling the transcriptome of
BMC Genomics, 2010 Background Freshwater planarians are an attractive model for regeneration and stem cell research and have become a promising tool in the field of regenerative medicine.
Fraguas Susanna +7 more
doaj +5 more sources