Results 41 to 50 of about 16,935 (240)

Stem cells and the Planarian Schmidtea mediterranea [PDF]

open access: greenComptes Rendus. Biologies, 2007
In recent years, stem cells have been heralded as potential therapeutic agents to address a large number of degenerative diseases. Yet, in order to rationally utilize these cells as effective therapeutic agents, and/or improve treatment of stem-cell-associated malignancies such as leukemias and carcinomas, a better understanding of
Alejandro Sánchez Alvarado
openalex   +3 more sources

Stepwise emergence of recombination suppression precedes fissiparous asexuality in the planarian Schmidtea mediterranea

open access: yesbioRxiv
Brand JN   +8 more
europepmc   +2 more sources

Chemical Exposure-Induced Developmental Neurotoxicity in Head-Regenerating Schmidtea mediterranea. [PDF]

open access: yesToxicol Sci, 2022
Abstract The growing number of commercially used chemicals that are under-evaluated for developmental neurotoxicity (DNT) combined with the difficulty in describing the etiology of exposure-related neurodevelopmental toxicity has created a reticent threat to human health.
Morris J   +6 more
europepmc   +3 more sources

Widespread maintenance of genome heterozygosity in Schmidtea mediterranea. [PDF]

open access: yesNat Ecol Evol, 2016
Loss of heterozygosity through inbreeding or mitotic errors leads to reductions in progeny survival and fertility. Loss of heterozygosity is particularly exacerbated in geographically isolated populations, which are prone to inbreeding depression and faster rates of extinction.
Guo L   +4 more
europepmc   +4 more sources

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