Results 221 to 230 of about 1,713,629 (338)

MiR-153-3p Suppresses Cell Proliferation, Invasion and Glycolysis of Thyroid Cancer Through Inhibiting E3F3 Expression [Retraction]. [PDF]

Onco Targets Ther
europepmc   +1 more source

Absorption of Broadband Low‐Frequency Sound Beyond the Thermodynamics Limit: An Acoustic Resonator With Magnetic Bearing

Advanced Science, EarlyView.
This work presents a magnetic‐bearing acoustic resonator that overcomes the thermodynamics limit of sound absorption. By introducing tunable negative stiffness, it achieves broadband low‐frequency absorption within a compact cavity, far exceeding the performance achievable by classic mass‐tuned designs.
Ying Hu, Zhe Zhang, Bohua Huang, Xue Han, Hallam Bastin Kilcoyne, Lixi Huang   +5 more
wiley   +1 more source

Rab1A-Mediated Exosomal Sorting of miR-200c Enhances Breast Cancer Lung Metastasis [Retraction]. [PDF]

Breast Cancer (Dove Med Press)
europepmc   +1 more source

PolyG Fibrils Coalesce Into Nuclear Ribbons That Engage Proteostasis Machinery in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong, Yongcheng Pan, Zhiyao Tang, Yuxuan Yao, Guicong Zhang, Junpu Wang, Haonan Xiao, Yun Tian, Beisha Tang, Dan Li, Qiang Guo, Ruijun Tian, Qiong Liu, Cong Liu   +13 more
wiley   +1 more source

The Pan-Inhibitor of Aurora Kinases Danusertib Induces Apoptosis and Autophagy and Suppresses Epithelial-to-Mesenchymal Transition in Human Breast Cancer Cells [Retraction]. [PDF]

Drug Des Devel Ther
europepmc   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

Cyclam-Modified Polyethyleneimine for Simultaneous TGFβ siRNA Delivery and CXCR4 Inhibition for the Treatment of CCl₄-Induced Liver Fibrosis [Retraction]. [PDF]

Int J Nanomedicine
europepmc   +1 more source

A Universal Protein Ladder for Standardization of Diverse FRET Assays

Advanced Science, EarlyView.
Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith, Katie L. Gelder, Lewis Hunter‐Craig, Daniel A. Bose, Timothy D. Craggs, Alison E. Twelvetrees   +5 more
wiley   +1 more source

Alisertib Induces Cell Cycle Arrest and Autophagy and Suppresses Epithelial-to-Mesenchymal Transition Involving PI3K/Akt/mTOR and Sirtuin 1-Mediated signaling pathways in Human Pancreatic Cancer Cells [Retraction]. [PDF]

Drug Des Devel Ther
europepmc   +1 more source

Chronic HBV Infection Disrupts CCL5‐Secreting cNK Cells and Attenuates Liver Accumulation and Activation of DCs and HBV‐Specific T Cells

Advanced Science, EarlyView.
ADORA2A activation suppresses NFκB‐dependent CCL5 production in cNK cells during chronic HBV infection, disrupting intrahepatic DC recruitment and HBV‐specific CD8+ T‐cell differentiation and function. Targeting the ADORA2A/NFκB/CCL5 axis restores antiviral immunity and facilitates HBV clearance.
Ailu Yang, Yucan Wang, Yating Yu, Jing Wu, Cuiping Bao, Zixuan Wang, Qiuju Han, Zhigang Tian, Jian Zhang, Huajun Zhao   +9 more
wiley   +1 more source