Results 221 to 230 of about 18,455,039 (345)

Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood

Advanced Science, EarlyView.
ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li, Xuanyue Ma, Zhenyu Ding, Bang Sun, Linglin Liu, Hei Matthew Yip, Wei Wang, Tianying Wu, Yuan Guo, Yinghui Peng, Shiqing Zhang, Jacque Pak Kan Ip, Li Zhang, Keshen Li, Lei Shi   +14 more
wiley   +1 more source

Asthma diagnosis in school-age children: a survey among Swiss physicians

Guerra Buezo B, Sasaki M, Leuenberger LM, Glick S, Gaillard EA, Moeller A, Regamey N, Sutter O, Goutaki M, Kuehni CE.   +9 more
europepmc   +1 more source

Preoperative interventions for reducing anxiety in school-age children undergoing surgery: a network meta-analysis. [PDF]

Cochrane Database Syst Rev
Martins Esteves I, Pires R, Pestana-Santos M, Sampaio F, Reis Santos M.   +4 more
europepmc   +1 more source

Community participation, supports, and barriers of school-age children with and without disabilities.

Archives of Physical Medicine and Rehabilitation, 2013
G. Bedell, W. Coster, M. Law, K. Liljenquist, Ying-Chia Kao, R. Teplicky, D. Anaby, M. Khetani   +7 more
semanticscholar   +1 more source

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

Advanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang, Mengying Yao, Jinhui Xie, Dingjie Wang, Yashi Shi, Xiaodan Mao, Chunhua Lu, Pengming Sun   +7 more
wiley   +1 more source

Association Between Hydration Status, Nutrition, and Cognitive Performance in School-Age Children in Kumasi, Ghana: A Cross-Sectional Study. [PDF]

Health Sci Rep
Commey NA, Anum JO, Daayi B, Martha NJT, Baah A, Tandoh MA.   +5 more
europepmc   +1 more source

Ischemic Postconditioning Protects Aged Myocardium Against Ischemia/Reperfusion Injury by Regulating Mitochondrial Dynamics via piR‐4913

Advanced Science, EarlyView.
A tiny RNA tips the scales of cardiac injury in aging. piR‐4913 recruits OGT to Drp1 and drives its O‐GlcNAcylation at Thr604, promoting excessive mitochondrial fission that aggravates ischemia‐reperfusion injury. Ischemic postconditioning silences this pathway to restore mitochondrial balance and protect the aged myocardium, revealing piR‐4913 as a ...
Xiangyu Zhao, Yanchun Li, Nan Li, Juan Zhang, Xiaolong Ma, Fei Yang, Ruihan Long, Yining Tian, Yichen Wang, Shengchao Ma, Huiping Zhang, Yideng Jiang   +11 more
wiley   +1 more source

Artificial intelligence-based quantitative analysis of interocular retinal vascular differences in school-age children with mild to moderate anisometropia. [PDF]

Front Med (Lausanne)
Xu Z, Ji Y, Hu Y, Tao Z, Lv Z, Hu G, Li M, Wang X, Deng H, Kang Z.   +9 more
europepmc   +1 more source

Disrupted Top‐Down Modulation as a Mechanism of Impaired Multisensory Processing in Autistic Children

Advanced Science, EarlyView.
In this work, we show that multisensory integration in autistic children is characterized by attenuated ERP responses and α‐band desynchronization, together with reduced theta‐band communication between parieto‐occipital and frontal regions. The intermediate neural profile observed in unaffected siblings raises the possibility that altered cortical ...
Theo Vanneau, John J. Foxe, Shlomit Beker, Sophie Molholm   +3 more
wiley   +1 more source

Associations between early childhood appetitive traits and dietary diversity in school-age children: a two-year longitudinal follow-up study. [PDF]

Front Nutr
Mu Y, Bu D, Xu X, Yuan J, Dai X, Lv W, Liu Y, Tang J, Zhang L, Jin Y.   +9 more
europepmc   +1 more source