Results 71 to 80 of about 18,573,716 (306)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Abstracts: 2013 GMDB - 49th Meeting of the Brazilian Group of Dental Materials

open access: yesBrazilian Journal of Oral Sciences, 2009
All abstracts appear as submitted by the authors without editing.
Brazilian Group of Dental Materials UNICAMP - Piracicaba Dental School
doaj   +1 more source

University High Highlights 1/15/1964 [PDF]

open access: yes, 1963
This is the student newspaper from University High School, the high school that was on the campus of Western Michigan University, then called University High Highlights, in ...
, University High School
core   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

University High Highlights12/13/1961 [PDF]

open access: yes, 1961
This is the student newspaper from University High School, the high school that was on the campus of Western Michigan University, then called University High Highlights, in ...
, University High School
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

PARADIGMA PENDIDIKAN UNTUK PEMBANGUNAN YANG BERKELANJUTAN DI TONGYEONG-SI, GYEONGSANGNAMDO, KOREA SELATAN

open access: yesJurnal Filsafat, 2016
Education for sustainable development has become global paradigm recently. This paradigm is a form of dynamic response and debate faced by the global community such as global warming, energy crisis, climate change, food security, as well as environmental
Hastangka Hastangka
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

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