Results 61 to 70 of about 770,313 (314)

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah   +6 more
wiley   +1 more source

What Would it Cost to Coach Every New Principal? An Estimate Using Statewide Personnel Data

open access: yesEducation Policy Analysis Archives, 2014
In this paper, I use Levin and McEwan’s (2001) cost feasibility approach and personnel data obtained from the Superintendent of Public Instruction to estimate the cost of providing coaching support to every newly hired principal in Washington State ...
Chad R. Lochmiller
doaj   +1 more source

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐based Health Systems Analysis

open access: yesArthritis Care &Research, Accepted Article.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada between 2014 and 2023.
Timothy S.H. Kwok   +7 more
wiley   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

open access: yesAdvanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad   +2 more
wiley   +1 more source

Non‐Invasive Brain Targeted Delivery of Cannabidiol for Alleviating Neuroinflammatory Disease

open access: yesAdvanced Materials, EarlyView.
The glucose‐functionalized nanoparticles (GNPs) are developed for the brain‐targeted delivery of cannabidiol (CBD). GNPs bypass the blood‐brain barrier (BBB) via glucose transporter‐1 (GLUT‐1) and release CBD in response to reactive oxygen species (ROS).
Yibin Wang   +7 more
wiley   +1 more source

Development of Nanoflare Nanosensors for Monitoring Cellular Insulin mRNA in Beta Cells and Islets

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents the design and application of In2‐NF probes for detecting insulin mRNA in beta cells and islets. Using spherical nucleic acid‐coated gold nanoparticles, the probes offer strong fluorescent signals upon hybridization. Their performance is validated across 2D and 3D cultures and rat islets, demonstrating sensitive, real‐time mRNA ...
Yana Hu   +7 more
wiley   +1 more source

HOSPITAL AND TRAINING SCHOOL ADMINISTRATION [PDF]

open access: yesAJN, American Journal of Nursing, 1913
n ...
openaire   +1 more source

Tunable Applicator for Microneedle‐Based Medical Devices

open access: yesAdvanced Materials Technologies, EarlyView.
This paper presents a simple, low‐cost tunable applicator (TAPP) for microneedle array patches that uses a material‐agnostic controlled‐fracture mechanism to ensure reliable skin penetration and uniform array engagement. The scalable, modular design is compatible with injection molding and 3D printing, can be integrated directly into patches, and is ...
Dan Ilyn   +9 more
wiley   +1 more source

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

open access: yesAdvanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang   +10 more
wiley   +1 more source

PROBLEMS ENCOUNTERED BY FEMALE SCHOOL PRINCIPALS IN TURKEY [PDF]

open access: yesIstraživanja u Pedagogiji
In this study, the problems faced by women principals in school administration were investigated. Phenomenology model was preferred in the study. The study group consisted of 17 female school principals working in public state schools in five central ...
İhsan Topcu   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy