Results 41 to 50 of about 1,534,833 (311)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Characteristics and outcomes of individuals screening positive for borderline personality disorder on an adult inpatient psychiatry unit: a cross-sectional study

BMC Psychiatry
Background Outpatient psychotherapies are gold standard interventions for borderline personality disorder (BPD); however, in clinical reality, higher rates of psychiatric hospitalization and more severe symptoms, including suicidality and self-harm ...
Joann J. Chen, Sam A. Mermin, Lucie A. Duffy, Samantha A. Wong, Savannah D. Layfield, Fernando Rodriguez-Villa, Steven E. Gelda, Eliot M. Gelwan, Jane Eisen, Kerry J. Ressler, Lois W. Choi-Kain, Agustin G. Yip   +11 more
doaj   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Specific symptom change associated with ecological momentary assessments of intrusive trauma memories

NPP-Digital Psychiatry and Neuroscience
As the global prevalence of exposure to traumatic events rises, there is a growing need for accessible and scalable treatments for trauma-related disorders like posttraumatic stress disorder (PTSD).
Yara Pollmann, Kevin J. Clancy, Quentin Devignes, Boyu Ren, Milissa L. Kaufman, Isabelle M. Rosso   +5 more
doaj   +1 more source

Preventing anxiety and depression in adolescents: A randomised controlled trial of two school based Internet-delivered cognitive behavioural therapy programmes

Internet Interventions, 2014
The aims of the current study were to 1) establish the efficacy of two Internet-based prevention programmes to reduce anxiety and depressive symptoms in adolescents; and 2) investigate the distribution of psychological symptoms in a large sample of ...
Nora Wong, Lianne Kady, Louise Mewton, Matthew Sunderland, Gavin Andrews   +4 more
doaj   +1 more source

Test anxiety levels of board exam going students in Tamil Nadu, India [PDF]

, 2014
The latest report by the National Crime Records Bureau has positioned Tamil Nadu as the Indian state with highest suicide rate. At least in part, this is happening due to exam pressure among adolescents, emphasizing the imperative need to understand the ...
Franklin, Gregory, Marslin, Gregory, Mary, Revina Ann, Sheeba, Caroline Jeya   +3 more
core   +4 more sources

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang, Lu Lu, Hui Gao, Qi Zhang, Jing Xiao, Josemir W. Sander, Weixi Xiong, Dong Zhou   +7 more
wiley   +1 more source

Multimodal prediction of future depressive symptoms in adolescents

BMC Psychiatry
Background Depression rates surge during adolescence. Early identification of youth at increased risk for depression is crucial for timely intervention and, ideally, prevention.
Linshanshan Wang, Ningxuan Zhou, Nigel M. Jaffe, Kristina Pidvirny, Anna O. Tierney, Hadar B. Fisher, Francesca Morfini, Erika E. Forbes, Diego A. Pizzagalli, Tianxi Cai, Christian A. Webb   +10 more
doaj   +1 more source

Methods and approaches to improving the emotional health and well being of children: A briefing paper concerning interventions to prevent internalising disorders [PDF]

, 2008
This paper presents a summary of the prevalence of somatic, anxiety and depressive disorders in children and of the known risk and protective factors associated with these problems.
Smith, Marjorie, Storey, Pamela
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source