Results 81 to 90 of about 1,367,590 (353)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
The Study of the Scale through Space. Teaching Innovation Experience among Architecture Schools: Malaga, Seville and Palermo [PDF]
, 2018 The educational innovation project object of this communication focuses on the scale problems that arise in the projects of territorial planning carried out in architecture schools, but also in the loss of the scale concept related to thought and ...
García Bujalance, Susana +2 more
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Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Espaces scolaires de la rentrée
Revue Internationale d’Éducation de Sèvres, 2013 Although generally governed by a distinction between learning and performance spaces, the spatial framework of the modern Danish secondary school also includes an intermediate situation which occurs at the start of the school year. In the three secondary
Henrik Reeh
doaj +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Design and implementation of a platform for smart connected school buildings [PDF]
, 2015 We have designed and implemented a platform that enables monitoring and actuation in multiple buildings, that has been utilised in the context of a research project in Greece, focusing on public school buildings.
Amaxilatis, D. +2 more
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Rafael Maldonado Tapias: un símbolo de la arquitectura escolar en Colombia
Dearq, 2012 Rafael Maldonado Tapias: architect and graduate of the Universidad Nacional de Colombia, and lecturer in Architectural Design. He completed his postgraduate degree in school architecture and wrote his dissertation on Buildings for primary school teaching
Camilo Augusto Muñoz Cadena +1 more
doaj
Les bâtiments scolaires, nœuds de relations
Revue Internationale d’Éducation de Sèvres, 2013 This article proposes a conceptual framework to enable an understanding of school construction practice and policy in the wider context of today’s education and society.
Geert Leemans
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Undergraduate dissertations in a department of architecture [PDF]
, 2005 Undergraduate academic writing in a Department of Architecture offers opportunities as well as challenges. To students, it can be a source of independent research and learning, enriching their development as architects and critics of the built ...
Romice, Ombretta, Yaneske, P.P.
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