Results 91 to 100 of about 11,454,205 (358)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Primary School Attendance and Completion Among Lower Secondary School Age Children in Uganda

open access: yesCurrent Issues in Education, 2013
At the World Education Forum in Dakar in 2000, governments pledged to achieve education for all by 2015. However, if current enrollment trends continue, the number of out-of-school children could increase from current levels.
Peter Moyi
doaj  

Prevalence and Factors Associated with Obesity among High School Children of District Shaheed Benazirabad [PDF]

open access: yesLiaquat National Journal of Primary Care
Background: Childhood obesity is a growing global health concern, affecting children across nearly all countries. Factors like socioeconomic status, urbanization, and genetic predisposition drive its rise. This alarming trend poses significant long-term
Shaista Sahito   +6 more
doaj   +1 more source

This Is Not a Myeloproliferative Neoplasm…

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

REVITALISASI SEKOLAH LUAR BIASA (SLB) PASCA IMPLEMENTASI PROGRAM PENDIDIKAN INKLUSI

open access: yesJurnal Penelitian Humaniora, 2015
Inclusion education is the education which incorporates children with special needs to learn with peers in regular schools. Extraordinary School is the one which is organized to serve school-age children with special needs (having a physical or mental ...
Slamet Hw, Joko Santosa
doaj  

Back pain in children associated with backpacks

open access: yesIndian Journal of Pain, 2015
Context: The school age children face daily responsibility of carrying variety of items to and fro and also around school. "Back pain" is currently emerging as a major health problem among school age group children, which can limit their daily activities.
Chandrashekhar D Aundhakar   +4 more
doaj   +1 more source

Enforcing the Educational Rights of Homeless Children and Youth: Focus on Chicago [PDF]

open access: yes, 1998
The obstacles facing homeless children and youth in securing a "free appropriate public education" are truly daunting. The frequent, often forced mobility of homeless families is a major barrier to maintaining their children's attendance at any ...
Laurene M. Heybach, Stacey E. Platt
core  

Home - About - Disclaimer - Privacy