Results 41 to 50 of about 11,018,435 (363)

Systematic review of the relationships between objectively measured physical activity and health indicators in school-aged children and youth.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2016
Moderate-to-vigorous physical activity (MVPA) is essential for disease prevention and health promotion. Emerging evidence suggests other intensities of physical activity (PA), including light-intensity activity (LPA), may also be important, but there has
V. Poitras, C. Gray, M. Borghese, V. Carson, J. Chaput, I. Janssen, P. Katzmarzyk, Russell R. Pate, S. Connor Gorber, M. Kho, M. Sampson, M. Tremblay   +11 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Learning to read in regular and special schools: a follow up study of students with Down Syndrome [PDF]

, 2015
In 2006, a questionnaire was sent to 160 parents of children with Down syndrome in Dutch primary education (special and regular) with a response rate of 76%.
De graaf, Gert, Van Hove, Geert
core  

Children’s Food and Drink Purchasing Behaviour ‘‘Beyond the School Gate’’ : The Development of a Survey Module [PDF]

, 2013
Copyright © 2013 Wendy J.Wills et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bromley, C., Craig, L.C.A., Macdiarmid, J. I., Masson, L.F., McNeill, G., Wills, Wendy   +5 more
core   +4 more sources

Breast Cancer and Aging: Understanding the Complex Relationship and Implications for Prevention and Screening

Aging and Cancer, EarlyView.
ABSTRACT Background Breast cancer is a multifactorial disease that affects many women worldwide. Age is the most important risk factor for breast cancer, with an increased incidence markedly after the age of 50. The relationships of aging to breast cancer have been thoroughly examined, and notable connections regarding various age‐related changes in ...
Mehran Radak, Armin Sharifi, Derek Richard, Hossein Fallahi   +3 more
wiley   +1 more source

A study of cardiovascular risk factors and its knowledge among school children of Delhi

Indian Heart Journal, 2014
Background: Data on the knowledge of cardiovascular risk factors among Indian school children are limited. Aim of the study was to assess the prevalence of cardiovascular risk factors and its knowledge among school children of Delhi.
Grace Mary George, Kamlesh Kumari Sharma, Sivasubramaniam Ramakrishnan, Sanjeev Kumar Gupta   +3 more
doaj   +1 more source

Pre-school enrollment: an analysis by immigrant generation [PDF]

, 2004
There has been minimal research on the pre-school enrollment of immigrant children. Using 1990 U.S. Census data, this paper investigates pre-school enrollment of child immigrants, those who immigrated as children and the U.S.-born children of ...
Chiswick, B., DebBurman, N.
core  

Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague, Kristin Engelstad, Yue Ge, Amber Tucker, Shufang Li, Jasim Uddin, Ziwei Zhao, John L. P. Thompson, Michio Hirano   +8 more
wiley   +1 more source

Obesity prevention for junior high school students: An intervention programme [PDF]

, 2013
Background: Generally, schools are an important setting to provide programmes for obesity prevention for children because the vast majority of children attend school. This study investigates how an intervention programme in the school subject of Physical
Dafopoulou, GM, Topalidou, A
core   +1 more source