Results 101 to 110 of about 3,904,190 (289)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

'I'd have to fight for my life there': a multicentre qualitative interview study of how socioeconomic background influences medical school choice. [PDF]

Med Educ Online, 2022
Rees EL, Mattick K, Harrison D, Rich A, Woolf K.   +4 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Invisible parenting? Middle-class choice within schools in Denmark

Education Inquiry
When given school choice, middle-class parents are known to use various strategies that increase segregation. This has also been observed in Nordic countries despite their belief in equality and the norm of children’s autonomy.
Rikke Brown, Jakob Ditlev Bøje
doaj   +1 more source

El proceso de valoración de los centros educativos por parte de las familias de clase media. El papel del orden expresivo en la búsqueda de la «distinción»

Papers, 2011
El presente artículo analiza la valoración que realizan las familias de clase media sobre el orden expresivo de distintos centros educativos. La composición social del alumnado, el proyecto educativo, la titularidad y el ambiente general son aspectos ...
Antonio José Olmedo Reinoso, Luis Eduardo Santa Cruz Grau   +1 more
doaj   +1 more source

School Choice, Teachers' Work, and Professional Identity. [PDF]

Educ Policy Anal Arch, 2022
Castro AJ, Jabbar H, Núñez Miranda S.
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Choice without Inclusion?: Comparing the Intensity of Racial Segregation in Charters and Public Schools at the Local, State and National Levels

Education Sciences, 2019
We conduct descriptive and inferential analyses of publicly available Common Core of Data (CCD) to examine segregation at the local, state, and national levels.
Julian Vasquez Heilig, T. Jameson Brewer, Yohuru Williams   +2 more
doaj   +1 more source

School Choice, Exclusion, and Race Taming in Milwaukee: A Meta-ethnography. [PDF]

Urban Rev, 2021
Hurie AH.
europepmc   +1 more source

The Impact of Advocacy Funding on the School Choice Debate [PDF]

, 2008
In this brief, the funding sources of school choice advocates and opponents and their potential impact on policy are examined.
Wendy C. Chi
core   +1 more source