Results 51 to 60 of about 743,685 (257)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

School choice and information

Estudios de Economía, 2012
Uno de los pilares detrás del sistema chileno de vouchers es que la competencia entre escuelas por atraer alumnos debiera conducir a mejoras en la calidad de la educación. Encuestas a padres de familia indican que los padres desconocenel desempeño de las
Daniel Gómez, Rómulo A. Chumacero, Ricardo D. Paredes   +2 more
doaj   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Changes in Rates of Uncontrolled Hypertension Among Federally Qualified Health Center Patients, 2019 to 2022: State-Level Group-Based Trajectory Modeling Analysis

Journal of Primary Care & Community Health
Background: The COVID-19 pandemic disrupted primary care and chronic disease management in the U.S., potentially affecting hypertension control differently across populations, particularly in patients with limited healthcare access.
Chaohua Li, Katherine Chung-Bridges, Megan D. Douglas, Kevin Espinoza, Mohamed Mubasher, Anne Gaglioti, Bryant Bailey, Dominic H. Mack, Peter T. Baltrus   +8 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

First-generation antipsychotic shortages in the United States: Utilization and switching patterns

Exploratory Research in Clinical and Social Pharmacy
Background: The United States Food and Drug Administration (FDA) has declared an increasing number of psychotropic shortages, which may adversely affect health outcomes by forcing psychotropic switches or rationing.
Ashley Tabah, Neel Swamy, Clayton English   +2 more
doaj   +1 more source

Virtual school parent perceptions of public school accountability

Discover Education
While school accountability systems were implemented to improve student outcomes through increased transparency, creating linkages between successful behaviors and rewards, they have often faced controversy.
Ian Kingsbury, David T. Marshall, Robert Maranto   +2 more
doaj   +1 more source

An Exploratory Analysis of U.S. Academically Intensive Charter Schools (AICS)

Education Sciences
Considerable amounts of research have discussed “No Excuses” charter schools preparing traditionally disadvantaged students for higher education. Yet, no scholarly work has identified or investigated U.S.
Robert Maranto, Jamison White, Sean Woytek   +2 more
doaj   +1 more source