Results 91 to 100 of about 3,338,488 (310)

Zur Bedeutung von Unterrichtsqualität für die naturwissenschaftliche Kompetenz von Grundschulkindern. Ein Fokus auf Kinder mit ungünstigen Lernvoraussetzungen [PDF]

, 2016
Research on classroom instruction has consistently identified characteristics that contribute to student learning. For instance, these include structural-organizational aspects (e.g., classroom management) and affective aspects (e.g., classroom social ...
Büttner, Gerhard, Decristan, Jasmin, Fauth, Benjamin, Hardy, Ilonca, Hertel, Silke, Kunter, Mareike   +5 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Compensatory education for disadvantaged Mexican students : an impact evaluation using propensity score matching [PDF]

The authors use propensity score matching to evaluate the effectiveness of CONAFE, a compensatory education program in Mexico, in improving student test scores and lowering repetition and failure rates.
Shapiro, Joseph, Trevino, Jorge Moreno
core  

"I cannot see my way clear. I cannot see the blackboard": Deconstructing personal failure stories [PDF]

, 2014
In this article, a failure identity story of a student counsellor is deconstructed. Self-data on the experiences of her six-year-old self in a school were generated through an outsider witness ceremony, as suggested by White (2007) in Maps of Narrative ...
Kotzé, Elmarie, Moneypenny, Paula Dian
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Perpetrating disaffection: Schooling as an international problem [PDF]

, 2008
This paper argues that, despite evidence of widespread disaffection, school is often regarded as the default position for educational provision, a given good. If there is disaffection with, and resistance to, schooling, then it is pupils and parents that
Harber, Clive
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

La transizione alla scuola superiore: modello teorico, costruzione e validazione della Scala di Difficoltà di Transizione (SDIT)

Journal of Educational, Cultural and Psychological Studies, 2010
High School Transition: Theoretical Underpinnings, Development and Validation of the Transition Difficulty Scale – SDIT The transition into senior high school is a critical juncture in the Italian education system and requires a challenging adaptation ...
Vega Scalera, Fabio Alivernini
doaj