Results 81 to 90 of about 3,336,539 (310)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Strategies of coping with school failure in students with mild intellectual disability in the inclusive model of education [PDF]
Nastava i VaspitanjeAcademic achievement refers to the student's degree of mastery of knowledge, intellectual and practical skills, and cognitive strategies and is a significant indicator of the degree of the student's adaptation to the school environment.
Krstić Katarina
doaj +1 more source
Evaluating the impact of Mexico's quality schools program : the pitfalls of using nonexperimental data [PDF]
The authors evaluate whether increasing school resources and decentralizing management decisions at the school level improves learning in a developing country. Mexico's Quality Schools Program (PEC), following many other countries and U.S. states, offers
Shapiro, Joseph, Skoufias, Emmanuel
core
Histories of school failure [PDF]
, 2015 Resumen: El fracaso escolar ha sido ampliamente investigado como fenómeno que atenta contra el bienestar y adecuado desarrollo de algunos chicos y chicas. Los resultados de dichos estudios muestran una gran variedad de factores implicados en su aparición
Martín Sánchez, Isabel Gema
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Eliminating Social Homelessness: Providing a Home to Grow [PDF]
, 2016 Middle school students who belong to marginalized identity groups often experience alienation and isolation. These feelings are compounded for multi-marginalized students who experience social homelessness–a term Harrison (2015) uses to describe students
Akos, Patrick +2 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Ensino médio para todos: oportunidades e desafios
Revista Brasileira de Estudos PedagógicosA pesquisa longitudinal de microdados de Censos da Educação Básica investigou o fluxo para o ensino médio de discentes do último ano do ensino fundamental na coorte 2008-2009.
Leonardo Claver Amorim Lima +1 more
doaj
Clio y AsociadosThe study analyses the family-school relationship at the secondary school stage in the educational centres of the Balearic Islands, Spain. In all cases, there is agreement on the scarce participation of families in the educational community.
Juan María González de la Rosa
doaj +1 more source
Choosing Between School Systems [PDF]
Hierarchical and comprehensive school systems are compared with respect to efficiency. At given ability, a student?s probability of not completing school rises with increasing mean ability in class. Both school systems can yield identical average failure
Volker Meier
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