Results 61 to 70 of about 1,716,087 (281)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Bedminster School postcard 1970 verso

, 1970
Postcard dated 1970 showing Bedminster School with the monuments for World War I and World War II in front. On verso are notes from Fred H. L. Field. "1970 Bedminster New Jersey War Monuments for World War I and II. Dr. Frank L. Field and his son Col.

core   +1 more source

Multiple thermal spin transport performances of graphene nanoribbon heterojuction co-doped with Nitrogen and Boron

Scientific Reports, 2017
Graphene nanoribbon is a popular material in spintronics owing to its unique electronic properties. Here, we propose a novel spin caloritronics device based on zigzag graphene nanoribbon (ZGNR), which is a heterojunction consisting of a pure single ...
Hai Huang, Guoying Gao, Huahua Fu, Anmin Zheng, Fei Zou, Guangqian Ding, Kailun Yao   +6 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

A brief history of the NPS Field Experimentation program: Spanning STAN, TNT and JIFX [PDF]

, 2014
The NPS Field Experimentation Program was initiated in FY02 to provide an opportunity for NPS faculty and students to evaluate new technologies from their research in a field environment.
Oros, Carl L.
core  

Molecular electronic chirality in copper phthalocyanine induced via twisted π-π stacking on bilayer graphene

Nature Communications
Electronic chirality within single molecules constitutes an intriguing phenomenon in quantum chemistry, whose inducing mechanism however remains underexplored.
Hao-Jun Qin, Rui-Jing Sun, Jia-Jun Liu, Wen-Ao Liao, Dao-Bo Wang, Jiang Yu, Tian-Hao Leng, Chao-Fei Liu, Wen-Hao Zhang, Ying-Shuang Fu   +9 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

FEM-based flow simulation of double-layer commingled production in gas reservoir-type gas storage

You-qi chuyun
ObjectiveMulti-layer commingled production is a common method for enhancing production efficiency in oil and gas reservoirs with varying physical characteristics.
Yuming LUO, Yuhan HU, Yulai PANG, Daoyong ZHOU, Siji CHEN, Ruihan ZHANG   +5 more
doaj   +1 more source