Results 31 to 40 of about 208,693 (266)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Implementation of agile approach in a reward-based crowdfunding project aimed at funding a film: An overview of the concept and challenges

open access: yesJournal of Economics and Management, 2019
Aim/purpose – The research aims to identify and evaluate factors impacting the implementation of an agile approach in a crowdfunding project with a goal to fund a film.
Świerczyńska-Kaczor Urszula   +2 more
doaj   +1 more source

TRENDS IN FILM INDUSTRY DEVELOPMENT IN POLAND

open access: yesHumanities and Social Sciences, 2018
The film industry in each country is referred to as "national cinematography". In Poland, very large changes in the cinematographic industry took place after 2005.
Agnieszka ORANKIEWICZ, Artur MAJER
doaj   +1 more source

SNS-CF: Siamese Network with Spatially Semantic Correlation Features for Object Tracking

open access: yesSensors, 2020
Recent advances in object tracking based on deep Siamese networks shifted the attention away from correlation filters. However, the Siamese network alone does not have as high accuracy as state-of-the-art correlation filter-based trackers, whereas ...
Thierry Ntwari   +3 more
doaj   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

open access: yesArthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni   +7 more
wiley   +1 more source

Language Practices within the Mixed Spanish-/Italian-/French- and Estonian-Speaking Families in Tallinn

open access: yesSocieties, 2022
This phenomenological study examined six mixed families living in Tallinn who are composed by French-/Italian-/Spanish-Estonian native speakers, who have at least one child who is being raised simultaneously with the combination of French-/Italian ...
Regina Seppik, Anastassia Zabrodskaja
doaj   +1 more source

Electrochemical Evaluation of Compressed Selective Laser Melted AlSi7Mg and AlSi10Mg Alloys in Chloride Environment

open access: yesAdvanced Engineering Materials, EarlyView.
The corrosion performance of AlSi7Mg and AlSi10Mg alloys produced through selective laser melting (SLM) was examined under compressive stress in a chloride environment. Electrochemical analyses, including open‐circuit potential (OCP), potentiodynamic polarization (CPP), and electrochemical impedance spectroscopy (EIS), were complemented by scanning ...
Femi John Akinfolarin   +2 more
wiley   +1 more source

Fast and Robust Object Tracking Using Tracking Failure Detection in Kernelized Correlation Filter

open access: yesApplied Sciences, 2020
Object tracking has long been an active research topic in image processing and computer vision fields with various application areas. For practical applications, the object tracking technique should be not only accurate but also fast in a real-time ...
Jungsup Shin   +3 more
doaj   +1 more source

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