Results 111 to 120 of about 8,007,578 (311)

Adolescent Mental Health and Teachers’ Health Literacy: A Mixed-Methods Exploration and Assessment of Coping and Support Mechanisms in Puducherry Schools

open access: yesNational Board of Examinations Journal of Medical Sciences
Background: Globally, adolescents face a significant mental health burden, with unique challenges in India. Teachers are pivotal in early identification and support but often lack adequate mental health literacy (MHL).
Manjubairavi T   +2 more
doaj   +1 more source

Volunteer Finds Voice [PDF]

open access: yes, 2012
Elizabeth Guzman ’14 found her calling in high school when she helped launch the Youth Advisory Council of the Oregon School-Based Health Care ...
Bouchard, Alison, \u2712
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Walking and Biking to School, Physical Activity and Health Outcomes [PDF]

open access: yes, 2009
Reviews research on the impact of walking or biking to school on children's physical activity and health outcomes, as well as factors affecting active transport to school, including improved sidewalk systems and neighborhood ...

core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Health Literacy: An overview of an emerging field [PDF]

open access: yes, 2011
According to the National Adult Literacy Survey, nearly 90 million American adults test below a high school level for literacy skills (Kirsch, Jungeblut, Jenkins & Kolstad, 1993).Because most health materials are written at least at the high school level,
Flaherty, Mary Grace
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Learning from the strengths of health care in schools in Brazil & opportunities for contemporary global school health

open access: yesGlobal Public Health
Most children and youth around the globe spend some time in school. Therefore, schools are essential for health, learning, and engaging families. School health models and programmes vary worldwide, some with strengths and weaknesses.
Lucine Francis   +2 more
doaj   +1 more source

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