Results 141 to 150 of about 17,211,696 (413)

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

open access: yesFEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Learning from the strengths of health care in schools in Brazil & opportunities for contemporary global school health

open access: yesGlobal Public Health
Most children and youth around the globe spend some time in school. Therefore, schools are essential for health, learning, and engaging families. School health models and programmes vary worldwide, some with strengths and weaknesses.
Lucine Francis   +2 more
doaj   +1 more source

Getting Communities Involved in Improving Sexual Health Education [PDF]

open access: yes, 2002
Since 1994, Public Education Network (PEN) has been working with local education funds (LEFs) to engage communities in developing comprehensive school health programs in public schools.

core  

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

Health concerns and health-risk behaviors among school-aged children in Saudi Arabia

open access: yesJournal of Family Medicine and Primary Care
Childhood and adolescence are profoundly important for the public health future. Children and adolescents experience rapid physical, physiological, and behavioral changes.
Ali Saad R. Alsubaie
doaj   +1 more source

Parental Perceptions of Oral Health and School-Based Dental Sealant Programs [PDF]

open access: yes, 2016
Introduction: Community Health Needs Assessment (University of Vermont Medical Center, 2013) Identified oral health in pediatric population as a primary concern Barriers to dental care cited: access, affordability, education School-Based Sealant Program (
Cole, Julie   +9 more
core   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

open access: yesFEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Functional parameters of spermatozoa obtained by a new selection device

open access: yesFEBS Open Bio, EarlyView.
This study compares density gradient centrifugation and the LensHooke CA0™ device for sperm separation. DGC requires multiple steps, specialized equipment, and technical expertise. In contrast, the CA0 device offers key practical and methodological advantages, resulting in a faster, simpler, and more affordable sperm selection method.
Julio C. Chávez   +8 more
wiley   +1 more source

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