Results 281 to 290 of about 3,148,879 (353)

Cytokine mRNA Delivery and Local Immunomodulation in the Placenta Using Lipid Nanoparticles

open access: yesAdvanced Therapeutics, EarlyView.
This article evaluates lipid nanoparticles to deliver immunomodulatory mRNA to placental cells and mouse placentas to study and treat the immune underpinnings of placenta‐related diseases. Lipid nanoparticles induce cytokine secretion and macrophage polarization toward an anti‐inflammatory state.
Samuel I. Hofbauer   +9 more
wiley   +1 more source

The Promise of School-Based Health Centers to Enhance Youth Mental Health Equity. [PDF]

open access: yesJ Sch Health
Bowen AE   +4 more
europepmc   +1 more source

Effect of Co and Mn Doping on the Electronic and Magnetic Properties of XC₂ (X = Hf, Zr) MXene Monolayers: A First‐Principles Study

open access: yesAdvanced Theory and Simulations, EarlyView.
The electronic and magnetic properties of Co and Mn doped Hf₂C and Zr₂C MXene monolayers are investigated using first principles DFT+U calculations. Doping significantly modifies both the electronic structure and magnetic behavior, with bandgap opening that may be suitable for infrared applications.
Emre Bölen, Meryem Derya Alyörük
wiley   +1 more source

SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1‐Mediated Transactivation of CD47

open access: yesAdvanced Science, EarlyView.
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu   +14 more
wiley   +1 more source

Non‐Invasive Diagnosis of Chronic Myocardial Infarction via Composite In‐Silico‐Human Data Learning

open access: yesAdvanced Science, EarlyView.
This study presents a non‐invasive machine learning model to identify infarct regions in the left ventricle using cardiac strain data. By combining rodent‐based simulated data with limited human data, the model achieves high accuracy in predicting infarct size and location without the need for gadolinium contrast agents, offering a promising ...
Rana Raza Mehdi   +7 more
wiley   +1 more source

Early School Medicaid Expansions and Health Services for Children With Parental Opioid Use Disorder.

open access: yesJAMA Health Forum
Meinhofer A   +3 more
europepmc   +1 more source

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