Cytokine mRNA Delivery and Local Immunomodulation in the Placenta Using Lipid Nanoparticles
This article evaluates lipid nanoparticles to deliver immunomodulatory mRNA to placental cells and mouse placentas to study and treat the immune underpinnings of placenta‐related diseases. Lipid nanoparticles induce cytokine secretion and macrophage polarization toward an anti‐inflammatory state.
Samuel I. Hofbauer+9 more
wiley +1 more source
The Promise of School-Based Health Centers to Enhance Youth Mental Health Equity. [PDF]
Bowen AE+4 more
europepmc +1 more source
The electronic and magnetic properties of Co and Mn doped Hf₂C and Zr₂C MXene monolayers are investigated using first principles DFT+U calculations. Doping significantly modifies both the electronic structure and magnetic behavior, with bandgap opening that may be suitable for infrared applications.
Emre Bölen, Meryem Derya Alyörük
wiley +1 more source
Leveraging existing market incentives to increase HIV pre-exposure prophylaxis access in the United States. [PDF]
Ratevosian J+3 more
europepmc +1 more source
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu+14 more
wiley +1 more source
Insights Into the Expectations of Infertile Men Regarding Multidisciplinary Reproductive Health Services. [PDF]
Abdullahzadeh M+3 more
europepmc +1 more source
Non‐Invasive Diagnosis of Chronic Myocardial Infarction via Composite In‐Silico‐Human Data Learning
This study presents a non‐invasive machine learning model to identify infarct regions in the left ventricle using cardiac strain data. By combining rodent‐based simulated data with limited human data, the model achieves high accuracy in predicting infarct size and location without the need for gadolinium contrast agents, offering a promising ...
Rana Raza Mehdi+7 more
wiley +1 more source
Early School Medicaid Expansions and Health Services for Children With Parental Opioid Use Disorder.
Meinhofer A+3 more
europepmc +1 more source
Availability and utilization of sexual and reproductive health services among adolescents of Godawari Municipality, Nepal: A cross-sectional study. [PDF]
Gautam L+3 more
europepmc +1 more source