Results 161 to 170 of about 3,591,556 (312)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Overnight Motor Memory Consolidation in Adolescents: Effects of Change in Dim Light Melatonin Onset After Sleep Restriction. [PDF]

J Biol Rhythms
Stager L, Gredvig-Ardito C, Crowley S, Seifer R, Carskadon M, Saletin J.   +5 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Enhancing Emergency Trauma Management Skills Through Simulation: A Quality Improvement Initiative in Ghana. [PDF]

Cureus
Dike NO, Okyere P, Kajjimu J, Achampong EK.   +3 more
europepmc   +1 more source

School Improvement Partner reports : advice and guidance on the writing and quality assurance of School Improvement Partner reports [PDF]

, 2007

core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Corrigendum to 'Prompt-Driven ChatGPT Carbon Calculator for Dental Practices: Estimation and Tailored Improvement Strategies' [Volume 76, Issue 1, February 2026, 103979]. [PDF]

Int Dent J
Duane B, Ashley P, Larkin J.
europepmc   +1 more source

Consultation document on the School Improvement Partner Programme [PDF]

, 2010

core  

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

HQ11: Does EMS (Electrical Muscle Stimulation) Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty. [PDF]

Geriatr Gerontol Int
Ogawa S, Wakabayashi H, Suzuki N, Jinno M, Inoue T, Maeda K, Yamamoto K, Rakugi H, Akishita M, Arai H.   +9 more
europepmc   +1 more source