Results 61 to 70 of about 17,811,962 (310)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Enhancing School Management Efficiency through Digital Classroom Management: A Comparative Study of Kenya and Indonesia

open access: yesTarbawi
This study investigates and compares digital classroom management practices in Kenya and Indonesia, with particular attention to the extent to which digital tools contribute to the efficiency of school management and instructional processes.
Alwy Ahmed Mohamed   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

01 Considerations of Public Management Functions - the Example of the College of Art "Ciprian Porumbescu" Suceava

open access: yesInternational Journal of Social and Educational Innovation, 2019
This study presents the basic functions of public management and summarizes the main duties of a school principal, as determined by the rules of organization and operation of schools approved by Order No.
Ciprian Ionel HRETCANU
doaj  

Reconseptualizing School Facility Governance through Tri Hita Karana-Based Strategic Management: A Qualitative Case Study in Denpasar, Indonesia

open access: yesTarbawi
This study interrogates the limited integration of culturally grounded ethics within dominant models of school facility management, which remain largely technocratic and efficiency-driven.
Ni Wayan Ary Rusitayanti   +2 more
doaj   +1 more source

Organizational growth and management overhead [PDF]

open access: yes, 1987
Supported by the organizations who participate in the Program in Systems Thinking. Supported by the New Management Style at the Sloan School of Management, MIT.by Peter Senge and Nathan ...

core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The importance of corporate branding in school management [PDF]

open access: yesStrategic Management, 2017
Corporate branding in school management is a relatively new term. The basic element of the marketing process of education makes the service itself, i.e. employees in education. This paper analyzes the role of employees in the construction of a brand that
Jukić Dinko
doaj  

Changes in the field of R&D management over the past 20 years [PDF]

open access: yes, 1989
"Paper delivered at the R&D Management Association Conference on the State of the Art in R&D Management, Manchester Business School, July 11-13, 1988."--p. 1.Includes bibliographical references.Thomas J.

core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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