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Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
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Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth +8 more
wiley +1 more source
Teacher-principal assessment of principal performance in selected secondary schools of Oklahoma /
Gaut, Robert Neal,
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The Indian Journal of Pediatrics, 2005
Education is one of the most important aspects of human resource development. Poor school performance not only results in the child having a low self-esteem, but also causes significant stress to the parents. There are many reasons for children to under perform at school, such as, medical problems, below average intelligence, specific learning ...
Sunil, Karande, Madhuri, Kulkarni
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Education is one of the most important aspects of human resource development. Poor school performance not only results in the child having a low self-esteem, but also causes significant stress to the parents. There are many reasons for children to under perform at school, such as, medical problems, below average intelligence, specific learning ...
Sunil, Karande, Madhuri, Kulkarni
openaire +2 more sources
Publishing School Performance Data
European Education, 2000The second Trouw publication (June 1998) on school performance in secondary education provoked much less discussion than the first, which appeared in the fall of 1997. Hitherto the two most important elements in the discussion were whether it was advisable to publish school performance data, and whether the grading technique used by Dronkers was ...
Bosker, R. J., Scheerens, J.
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