Results 51 to 60 of about 2,884,071 (256)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

La cultura de la ciencia: contribuciones para desarrollar competencias de pensamiento científico en un encuentro con la diversidad

open access: yesRevista Científica, 2011
The present article emphasizes on the importance and the role of the sciences, as complex human activities, in the field of applications inside the school context, keeping in mind the values of the pupil and the objec- tives of the school.
SILVIO DAZA ROSALES   +2 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

School Administrators’ Opinions on Providing Freedom of Science in Science High Schools

open access: yesInternational Journal of Educational Leadership and Management
This study aimed to determine the views of school administrators regarding the provision of freedom of science in science high schools, the challenges they faced in exercising this freedom, and potential solutions to these challenges.
Emel Yilmaz   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

KETERAMPILAN PROSES SAINS DAN PEMBELAJARAN IPA DI SEKOLAH DASAR (TELAAH BUKU SISWA KELAS IV SD TEMA 2 KARYA SUMINI)

open access: yesProfesi Pendidikan Dasar, 2016
The purpose of this research was to determine aspects of applied learning approach based on science process skills as a way to transfer material science for students in elementary school. The method used is the method of library research.
Anatri Desstya
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Student’s Science Literacy in Science Learning at Elementary School

open access: yesLectura: Jurnal Pendidikan
This study aims to describe literacy in science learning in elementary schools. This study uses a type of qualitative research. This research was conducted at SDN 1 Karangsari which is located in Karangsari Village, Kec. Rowosari, Kab.
Rizky Cahyaningtyas, Anatri Desstya
doaj   +1 more source

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