Results 101 to 110 of about 1,653,633 (311)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
آموزش بهداشت و ارتقاء سلامت ایران, 2013 Background and objective: Imagining the world without computers is getting harder and harder every day. They play an important role in scientific improvement and public access to information. Children and youngsters who use computers in the virtual world
Rabiallah farmanbar +3 more
doaj
Exploring Fijian high school students’ conceptions of averages
, 2008 This paper focuses on part of a much larger study that explored form five (14 to 16 year-old) students’ ideas in statistics. A range of ideas was explored, including the students’ ideas about measures of centre and graphical representations.
Sharma, Sashi
core
School choice and student wellbeing
Economics of Education Review, 2014 The debate over private versus public provision of schooling remains contentious. A large literature has developed focusing on the relative educational performance of different school types. Beyond these important outcomes, variations in schooling may have direct effects on students’ contemporaneous welfare.
Green, Colin +3 more
openaire +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Responding to rewards and sanctions: the impact on students’ sense of belonging and school affect
, 2007 This qualitative study examines the impact of students’ interpretations and responses to rewards and sanctions on sense of belonging and school affect.
Mansfield, C.
core
Mired in the shadows: quiet students in secondary schools
, 2011 Quiet students are a feature of the organisation of secondary schools. Using qualitative methods and Deleuzean conceptualisations of modern subjectivity, this paper explores the ways that quiet students negotiate the terrain of their school.
James Bell +5 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source