Results 131 to 140 of about 12,718,765 (297)

Protocol for a mixed-methods pilot study on the feasibility of TABATA training to alleviate moderate to severe psychological stress in Chinese middle school students

Frontiers in Psychology
Chinese secondary school students face increasingly complex psychological stress. Traditional interventions for adolescent psychological stress usually focus on psychological counseling or medication.
Li Hao, Li Hao, Arimi Fitri Mat Ludin, Mahadir Ahmad, Zhang Ben   +4 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Prevalence of Intestinal Parasitic Infections Among Students Attending Schools in La'elay Maichew District, Tigray Region, Ethiopia

Health Science Reports
Background and Aims Intestinal parasitic infections (IPIs) remain a significant public health challenge across Ethiopia, including the Tigray region, where school‐age children (SAC) are particularly vulnerable. The La'elay Maichew district, characterized
Teklay Abrha Yanshet, Gebremedhin Gebrezgabiher, Melese Birmeka   +2 more
doaj   +1 more source

Comparative analysis of the diffusion trends of e-cigarette use and cigarette smoking among school students in China: a cross-sectional study

Zhongguo gonggong weisheng
ObjectiveTo explore the influencing factors of and differences in cigarette smoking and e-cigarette use among school students in four typical cultural regions (Yangtze River Delta, Pearl River Delta, southwestern China, and northern China) of China, thus
Nan WU, Rong DING, Xiaozhao YANG
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Insight into Body Mass Index among School Students during the COVID-19 Pandemic

Dr. Sulaiman Al Habib Medical Journal
Background: Several reports indicate that extended stay at home for online school as a result of the coronavirus disease 2019 (COVID-19) pandemic or other reasons may change the normal physical activity and body weight of school-age students.
Amjad Alfaleh, Abdullah Alkattan, Fatemah Almutairi, Mona Almutairi, Khlood Sagor, Mody Abdulhai, Alaa Alageel, Khaled Alabdulkareem   +7 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

First School Reunion 1978

, 1978
1978 yearbook copied for school ...
George Clem School
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source