Results 41 to 50 of about 316,082 (266)

Project Initiation Document Phase One: Scoping Exercise within special schools [PDF]

, 2014
This Project Initiation Document outlines the purpose and plan of Phase One of the Review of AHP Support for Children with Statements of Special Educational Needs in Special Schools and Mainstream ...
Public Health Agency
core   +1 more source

Master of Public Health Concentrations in Global Health in 2020: Preparing Culturally Competent Professionals to Address Health Disparities in the Context of Globalization [PDF]

, 2021
During the 2019-2020 academic year, 37 (17%) of 223 Council on Education for Public Health (CEPH) accredited or applicant schools and programs of public health offered Master of Public Health (MPH) degrees with concentrations in general global health ...
Malouin, Rebecca, Waggett, Caryl E., Zeraye, Helen A., Jacobsen, Kathryn H., Gartin, Meredith, Bisesi, Michael S.   +5 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Protocol for a systematic review of the effects of schools and school-environment interventions on health: evidence mapping and syntheses. [PDF]

, 2011
BACKGROUND: Schools may have important effects on students' and staff's health. Rather than treating schools merely as sites for health education, 'school-environment' interventions treat schools as settings which influence health.
Moore, L., Campbell, R., Whitehead Margaret, Moore, Laurence Anthony Russell, Angela Harden, Margaret Whitehead, Jamal, F., Mark Petticrew, Moore, L, Thomas, James, Bonell Chris, Petticrew, M., Petticrew, M, Bonell, C., Wells, H, Helene Wells, Chris Bonell, Harden, A, Wells, Helene, Harden Angela, Fletcher Adam, Harden, A., Fletcher, A., Jamal Farah, Campbell Rona, Moore, Laurence, Jamal, Farah, Petticrew, Mark, Thomas, J., Wells Helene, Simon Murphy, Jamal, F, Murphy Simon, Campbell, R, Whitehead, Margaret, Petticrew Mark, Farah Jamal, Murphy, Simon, Murphy, S., Fletcher, A, James Thomas, Bonell, C, Rona Campbell, Thomas James, Fletcher, Adam, Laurence Moore, Moore Laurence, Bonell, Chris, Whitehead, M., Wells, H., Harden, Angela, Whitehead, M, Campbell, Rona, Adam Fletcher, Thomas, J, Murphy, S   +55 more
core   +1 more source

Investigating selected host and parasite factors potentially impacting upon seasonal malaria chemoprevention in Bama, Burkina Faso

Malaria Journal, 2020
Background Since 2014, seasonal malaria chemoprevention (SMC) with amodiaquine–sulfadoxine–pyrimethamine (AQ–SP) has been implemented on a large scale during the high malaria transmission season in Burkina Faso.
Fabrice A. Somé, Thomas Bazié, Hanna Y. Ehrlich, Justin Goodwin, Aine Lehane, Catherine Neya, Kabré Zachari, Martina Wade, Jean-Marie Ouattara, Brian D. Foy, Roch K. Dabiré, Sunil Parikh, Jean-Bosco Ouédraogo   +12 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Community Education Needs to be Supported by Strong Public Policy to Tackle Food Poverty [PDF]

, 2008
Community education needs to be supported by strong public policy if it is to be fully effective at tackling food poverty and obesity, a project evaluation by the Institute of Public Health in Ireland (IPH) has found. In its evaluation of Decent Food for
Institute of Public Health in Ireland
core   +1 more source

Toward a public health leadership national training agenda: a review of conceptual frameworks and core competencies

Frontiers in Public Health
Strong and effective leadership is essential for the success of public health systems. It serves as the driving force that inspires, guides, and empowers individuals to improve the health of their communities and strengthen their organizations ...
Emily M. Burke, Jordan A. Fox, Kaitlin Tager, Sara McDowell, Fawn Phelps, Howard Koh   +5 more
doaj   +1 more source