Results 91 to 100 of about 9,175,674 (404)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Why is 100% Reserve Banking Inefficient? [PDF]

open access: yes
Financial crises are an important concern today. One part of the problem is banking crises, at the root of which is the bank run problem. One solution is 100% reserve banking. But this is inefficient. The reasons are, however, not obvious. The literature
Gurbachan Singh
core  

Racial Conflicts In Schools [PDF]

open access: yes, 2010
That racially motivated conflicts occur in schools is an indisputable fact that becomes evident upon review of both academic literature and popular media.
Martinez, Michael J
core   +1 more source

Improving Executive Functions at School in Children With Special Needs by Educational Robotics [PDF]

open access: gold, 2020
Maria Lieto   +7 more
openalex   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Corporate Governance, Competition and Firm Performance: Evidence from India. [PDF]

open access: yes
The aim of this paper is to show the interaction effect of product market competition and corporate governance variables on firm performance. While the linkage between internal governance mechanism and firm performance is well established in several ...
Manoj Pant   +1 more
core  

Getting real in the community: Evaluating the “making a difference” interdisciplinary social engagement project

open access: yesMedEdPublish, 2016
Purpose It is increasingly recognised that medical schools have a duty to the communities they serve, and that there are many benefits to be gained from student social engagement within those communities. There is also ongoing interest in the value of
Richard Ayres   +2 more
doaj  

Physical activity and the prevention, reduction, and treatment of alcohol and/or substance use across the lifespan (The PHASE review): protocol for a systematic review

open access: yesSystematic Reviews, 2018
Background Alcohol and substance use results in significant human and economic cost globally and is associated with economic costs of £21 billion and £15billion within the UK, respectively, and trends for use are not improving.
Tom P. Thompson   +10 more
doaj   +1 more source

School Pharmacist/School Environmental Hygienic Activities at School Site

open access: yesYAKUGAKU ZASSHI, 2016
The "School Health and Safety Act" was enforced in April 2009 in Japan, and "school environmental health standards" were established by the Minister of Education, Culture, Sports, Science and Technology. In Article 24 of the Enforcement Regulations, the duties of the school pharmacist have been clarified; school pharmacists have charged with promoting ...
openaire   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

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